Effectiveness of Algan Hemostatic Agent in Bleeding Control: An Experimental Kidney Incision Model
Journal Title: The Medical Bulletin of Haseki - Year 2021, Vol 59, Issue 1
Abstract
Aim: The purpose of this study is to evaluate the hemostatic efficacy of a novel plant originated blood stopper which is called Algan Hemostatic Agent (AHA) in uncontrolled kidney incision bleeding model. Methods: The study was conducted with thirty-two rats 5-7 weeks old. The rats were randomly divided into 4 groups, each consisting of eight rats (Group 1: heparinized saline, 2: heparinized AHA, 3: non-heparinized saline, 4: non-heparinized AHA). Experimental kidney incision was made, and saline soaked sponge was applied to the control group and AHA to the study group. Results: The duration of bleeding was significantly shorter in the AHA group compared to the control group. The AHA has controlled the bleeding in the heparinized and non-heparinized groups 5±1.19 and 3±0.91 seconds respectively (p<0.001). In the control group, hemorrhage was controlled in the heparinized and non-heparinized group 180.6±25.4 and 125.4±21 seconds respectively. Conclusion: This study demonstrated that the AHA is useful in controlling bleeding in the Rat kidney incision model.
Authors and Affiliations
Ahmet Midi, Ali Kumandaş , Hüsamettin Ekici, Yusuf Kılıç, Ruchan Özgöçmen
Keywords
Related Articles
- EP ID EP693382
- DOI 10.4274/haseki.galenos.2021.6506
- Views 97
- Downloads 0
Correlation of the Severity of Carotid Artery Stenosis Identified by 64 Detected CT using ‘‘CC’’ Method with Color Doppler Ultrasound Findings
Aim: The aim of this study was to investigate the correlation between the severity of carotid stenosis determined with 64-multidetector row computed tomographic angiography (CTA) (64-MDCTA) using the ‘‘common carotid’’ (...
Epidemiology, Diagnosis and Treatment of Acute Septic Arthritis in Haseki Orthopedics and Traumatology Clinic
Aim: Septic arthritis may represent a direct invasion of joint space by various microorganisms. The aim of this study was to determine the epidemiological characteristics of patients with septic arthritis in our clinic a...
Is Complement Factor H Tyr402His Variant a Potential Cause of Ankylosing Spondylitis?
Aim: Ankylosing spondylitis (AS) is an autoimmune disease caused by chronic inflammatory response. Complement system is the major component of the innate immune defence. In this study, we investigated the potential assoc...
Noncompliance with Dietary Salt Restriction and Outcomes in Chronic Heart Failure: A Propensity Score Matching Analysis from TREAT-HF Registry
Aim: To compare chronic heart failure patients with reduced ejection fraction (cHFrEF) who stated to comply with salt restriction in their diets versus those who did not. Methods: Patients without salt restriction were...
A Novel Frameshift Mutation in Two Siblings with Merosin-deficient Congenital Muscular Dystrophy
We present two siblings with elevated serum creatine kinase concentrations, developmental delay, muscle weakness, and contractures of the lower limbs. Cranial magnetic resonance imaging revealed diffuse white matter hype...