Effects of addition of dexmedetomidine to bupivacaine on the block characteristics of brachial plexus block by supraclavicular approach
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1
Abstract
Background: Dexmedetomidine, a non-opioid adjuvant to neural blockade supposed to improve the quality of nerve blockade. This study intends to compare the effects of addition of dexmedetomidine as an adjutant to bupivacaine for supraclavicular brachial plexus block. Methods: A prospective, double blinded, randomized control study was conducted on 60 adult patients scheduled to undergo elective upper limb orthopedic procedures under regional anaesthesia. The patients were divided into two groups by randomization. Group A patients received 30ml of 0.325% bupivacaine containing 0.3 ml of distilled water.Group B patients received 30ml of 0.325% bupivacaine containing 0.3 ml of dexmedetomidine (30 mcg). Onset of sensory, motor blockade, duration of sensory and motor blockade, duration of post-operative analgesia and adverse effects, if any, were observed. Results: Demographic profile between two groups of patients were comparable. Mean(SD) time of onset of sensory block and motor blockade between group A vs Group B were 10.37 ±2.86 vs 6.17±1.58, 15.93±2.30 vs 11.10±2.12 . Mean (SD) duration of sensory and motor blockade between group A vs Group B were 240.03 ±39.84vs 824.03± 38.05, 208.43± 33.47 vs 779.87± 32.91 . Mean (SD) Duration of post-operative analgesia was 271.60±37.92 vs 857.10 ±37.83 .Statistically highly significant difference was observed between Group A and Group B patients in terms of onset of sensory, motor blockade, duration of sensory, motor blockade and duration of post-operative analgesia (p<0.001) Conclusion: Dexmedetomidine added as an adjuvant to bupivacaine for supraclavicular brachial plexus block has superior quality of sensory and motor blockade with prolonged postoperative analgesia with negligible adverse events.
Authors and Affiliations
C S Prakash, S Vigneshwaran
Keywords
Related Articles
- EP ID EP440506
- DOI 10.26611/1015814
- Views 151
- Downloads 0
Efficacy of bupivacaine infiltration for postoperative pain relief in paediatric patients
Background: The effective control of pain remains one of the most important issues in the postoperative care today. Local infiltration of bupivacaine requires less skill and is better technique for postoperative pain rel...
Efficacy of dexmedetomidine infusion in patients undergoing tympanoplasty surgery under local anaesthesia
Background: Tympanoplasty is done under local anaesthesia using a microscope and require good surgical field visibility. Dexmedetomidine is a highly selective α2 adrenergic agonist used for analgesia and sedation, sympat...
Dexmedetomidine as epidural adjuvant to Ropivacaine in elective lower limb surgeries
Epidural adjuvants are used to prolong the action of local anesthetic agent so as to have prolongation of motor and sensory block. Dexmedetomidine a newer α2 agonistic agent with predominant affinity to α2receptor, α2:α1...
Intrathecal dexmedetomedine and magnesium sulphate as an adjuvants to hyperbaric bupivacaine in pregnancy induced hypertensive patients: A clinical comparative study
Background and Aims: Providing a safe anaesthesia and analgesia with a stable hemodynamic and with no neonatal adverse effects to a preeclamptic caesarean patients is a challenging task. Various adjuvants have been tried...
Comparison of intramuscular atropine and glcopyrrolate in children undergoing various surgical procedures under general anaesthesia
Background: Antiocholinergic premedication in paediatric patients undergoing surgeris under general anaesthesia plays in important role in blocking the potentially dangerous vagal reflexes and in also controlling the oro...