Effects of Intravascular Laser Irradiation of Blood on Cognitive Function in a Stroke Survivor with Hyperhomocysteinemia: Dual Recuperations in Thalamus and Serum Homocysteine
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 16, Issue 2
Abstract
Stroke is a major public health issue worldwide because of the high risk of unavoidable disability leading to a noteworthy burden of the patients themselves, the families and the society [1]. Cognitive impairment accounts for an important element of disability after stroke. Previous studies have shown a high prevalence of cognitive impairment in adults with stroke [2]. However, the pathophysiology of cognitive impairment has not been clarified yet. Hyperhomocysteinemia (HHcy) has been recognized as a risk factor for cardiovascular disease, stroke, vascular contributions to cognitive impairment and dementia, and Alzheimer’s disease [3]. Nonetheless, the published methods for reduction of serum homocysteine did not have promising results yet. Intravenous laser irradiation of blood (ILIB) is a mini-invasive approach to provide phototherapy for adults with stroke [4]. Whether cognitive impairment may recuperate as a consequence of ILIB intervention has not been determined. We report herein cognitive impairment in a stroke survivor with HHcy, and after ILIB, remarkable regression of initial cognitive impairment occurred together with reduction of serum homocysteine.
Authors and Affiliations
Jia Yu Chang, Chuan Ching Liu, I Ting Liu, Shin Tsu Chang
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