Effects Of Low Doses Of Intrathecal Clonidine And Dexmedetomidine With Bupivacaine On The Duration Of Sensory And Motor Block In Abdominal And Lower Limb Surgeries- A Prospective Randomised Double Blinded Study
Journal Title: International Journal of Health & Medical Research - Year 2024, Vol 3, Issue 05
Abstract
BACKGROUND: The purpose of this study is to compare the duration of sensory and motor block in elective lower limb and abdominal procedures following intrathecal administration of bupivacaine along with adjuvants either clonidine or dexmedetomidine. METHODS: A prospective randomised double blinded study. 120 study participants were randomly allocated to three groups-Group A was given 12.5 mg of hyperbaric bupivacaine, Group B was given 3 mcg dexmedetomidine along with 12.5 mg hyperbaric bupivacaine and Group C was given 30 mcg of clonidine along with hyperbaric bupivacaine. The duration of sensory and motor block was recorded. RESULTS: Group B and C study participants showed significantly longer duration of sensory and motor block when compared to Group A. The mean duration of sensory block in Group A was 92.5 minutes, Group B 124.5 minutes Group C (119.4 minutes) (A vs B, A vs C p<0.001). The mean duration of motor block in group A 149.1 min, group B 252.5 min, Group C 217 min (A vs B, A vs C, B vs C P<0.001) CONCLUSION: By adding 3 mcg dexmedetomidine or 30 mcg clonidine to hyperbaric bupivacaine duration of sensory and motor block was significantly prolonged.
Authors and Affiliations
Dr P Lekha Priyadharshini, Dr V Jayaraman
Keywords
Related Articles
- EP ID EP739995
- DOI 10.58806/ijhmr.2024.v3i05n01
- Views 46
- Downloads 0
Gastroesophageal Reflux Disease: Epidemiology, Pathogenesis and Therapeutic Approaches
Gastroesophageal reflux disease (GERD) is a disorder that is characterized by upward flux of gastric chyme into the oesophagus. It may happen with no erosion as retrograde flow disorder or can cause erosive esophagitis....
Anemia Risk Factor Model in Pregnant Women
The purpose of this study was to analyze the risk factors and variables that most influence the incidence of anemia in pregnant women at Tilango Health Center after controlling for maternal risk factors such as gestatio...
Management of Twin Pregnancies and The Risk of Fetal Death
Introduction: Twin pregnancies can present risks to both mother and fetus. One of the biggest concerns in twin pregnancies is premature birth. Objectives: To discuss the management of twin pregnancies in order to avoid...
PRF As An Alternative Membrane to Autogenous Gingival Graft in The Treatment for Gingival Recession
Gingival recession is a term when the marginal gingiva apically shifts from its normal position to the root surface level beyond the cementoenamel junction. Gingival recession can cause aesthetic and functional problems....
Application of Nanomedicine in Cancers: A Review
Nano-drugs have always been used as a new treatment for various cancers. Recently, many advances have been made in the use of nano-drugs, which has led to the introduction of nano-drugs as an important factor in the fron...