EFFECTS OF PROCESSED VIGNA SUBTERRANEA (BAMBARA GROUNDNUTS) SEEDS ON HEPATIC SERUM ENZYMES IN ALBINO WISTAR RAT
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 12
Abstract
Seventy Wistar albino rats were used in a 28 days feed trial to determine the impact of different processed seeds of Vigna subterranea on the levels of serum enzymes. There were seven (7) experimental groups each made up of ten rats, allocated to the experimental diets. In this study it was observed that rats fed with the different processed samples of Vigna subterranea significantly increased in weights of the rats at P<0.05. Haematological tests were also conducted and subsequent data revealed an increase (P<0.05) in the Packed cell volume (PCV), haemoglobin, Mean Corpuscular haemoglobin concentration (MCHC), and total red blood cell of the rats fed with different processed seeds of Vigna subterranea. This was accompanied with a significant increase in the total white blood cell of the rats fed with roasted and raw samples of Vigna subterranea as against other experimental groups when compared with the control group. Serum transaminases; aspartate transaminase and alanine transaminases (AST and ALT) and serum alkaline phosphatase (ALP) showed significant (p<0.05) increase in activity in the serum of rats fed with roasted and fermented samples of Vigna subterranea as against other experimental groups when compared with the control group.
Authors and Affiliations
Ukpanukpong R. U.
Keywords
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