Efficacy & Acceptibility of Azilsartan as Antihypertensive: A Clinical Evaluation in Magadh Zone of Bihar
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 2
Abstract
Introduction: Better control of hypertension while maintaining good quality of life with least side effect has always been the aim of antihypertensive therapy. Search for newer drugs continues and azilsartan has come up with so claimed improved quality. Aims and Objectives: To study the so claimed improved quality of azilsartanin terms of efficacy and acceptability. Material and Method: 2 doses of azilsartan (40 & 80 mg) is compared with 40 mg of olmesartan. 111 patients enrolled from the outdoor patients of Anugrah Narayan Medical College Hospital, Gaya randomized to three groups and clinic BP measurements recorded and analysed. Results: Azilsartan showed more reduction of both systolic and diastolic BP compared to olmesartan .Safety profile was comparable. Quality of life appears slightly better with azilsartan. Discussion: Many clinical trials also favours its superior efficacy. Azilsartan possesses very high affinity for angiotensin type II receptor (AT I R) with characteristically slow dissociation property Azilsartan also exhibits pleotropic effect making it better for cardio vascular and reno-protection. Conclusion: Azilsartan is a novel angiotensin receptor blocker. It exhibits all the good quality of ARB with superior efficacy.
Authors and Affiliations
Dr Pramod Kumar Sinha
Keywords
Related Articles
- EP ID EP486754
- DOI -
- Views 71
- Downloads 0
Evaluation the Role of Mobile Phone in Microbial Transmission to Nurses` Hands in Hospital Critical areas
Background: The use of cell phones often occurs in hospitals, by patients, visitors and health care workers, and this is one environment where hospital-associated infection is most prevalent. Aim: this study was carried...
Rosai Dorfman Disease –A Rare Presentation: Case Report
We present a case of Rosai Dorfman Disease of bilateral inguinal nodes, for its unusual presentation. We diagnosed it based on the characteristic cytological and histomorphological findings and confirmed it using Immunoh...
A study of PALM-COEIN Classification of Abnormal Uterine Bleeding (AUB) in Perimenopausal Women at a Tertiary Care Teaching Hospital
Background: AUB is the commonest menstrual problem of women of reproductive age group specially during perimenopause. It significantly impacts women’s personal, social, physical and quality of life. International Federat...
Clinical Study of Oral Manifestation in Skin Diseases at Tertiary Care Centre in Central India
The study aimed to estimate the frequency of oral lesions in Patient with Skin Manifestation attending a Tertiary Care Centre in Central India. An oral mucosal lesion (OML) is defined as any abnormal change or any swelli...
Synchronous Primary Endometrioid Type Endometrial & Ovarian Adenocarcinoma; A Rare Case Report
Synchronous primary endometrial and ovarian cancer (SEOC) is a relatively uncommon disease. It can be of similar or dissimilar histologies, is commonly diagnosed at younger age, early stage, low grade and have better pro...