Efficacy and safety of intravenous iron sucrose versus oral iron in pregnant women with mild to moderate iron deficiency anaemia
Journal Title: Santosh University Journal of Health Sciences - Year 2016, Vol 2, Issue 2
Abstract
Background: Efficient treatment of iron deficiency anaemia in pregnant women would lead to a considerable reduction in the risk factors, affecting maternal and fetal outcome. Patients and Methods: This prospective study was carried out in 84 women between 20 to 34 weeks of pregnancy with established iron deficiency anaemia and haemoglobin 6-10g/dL. They were randomised to receive either oral or intravenous iron in required dose. Haemoglobin and ferritin levels were measured at recruitment and after 4 weeks of therapy. Adverse drug reactions were also noted in both the groups. Results were analysed by student’s t-test. Results: The mean increase in haemoglobin values with IV sucrose group was 1.26 ±0.58g % as compared to 0.78 ±0.37 gm% in oral iron group after 4 weeks of oral iron therapy (p<0.03). Similarly, The mean increase in ferritin values with IV sucrose group was 12.00 ± 11.77ng/ml as compared to 6.50 ± 9.53ng/ml in oral iron group (p<0.02). Conclusion: This study indicates iron sucrose not only treats but also corrects iron stores which are not seen with oral iron.
Authors and Affiliations
Neelima Agarwal, Amita Sharma, Manisha Gupta, Alpana Agrawal
Keywords
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