Efficacy and Safety of Monopolar Transurethral Resection of the Prostate on Bleeding Control in the Treatment of Benign Prostatic Obstruction: Is It Still a Good Option in Developing Countries?

Journal Title: The Bulletin of Urooncology - Year 2020, Vol 19, Issue 3

Abstract

Objective: The objective of this study is to investigate the bleeding control safety along with the need for preoperative blood preparation and postoperative blood transfusion in the transurethral resection of the prostate with monopolar system (M-TURP) for the treatment of benign prostatic obstruction (BPO). Materials and Methods: We retrospectively analysed 379 patients with BPO who underwent M-TURP procedure between January 2016 and December 2019 at a single centre. Importantly, we collected the demographic data, use of 5-alpha-reductase inhibitor (5-ARI), postoperative haemoglobin (Hb) and haematocrit levels, platelet counts, and transfusion rates of these patients. Results: The minimum, maximum and the mean ages of the patients were 43, 79 and 67.44±7.74 years, respectively. The minimum, maximum and the mean prostate volumes of the patients measured via transrectal ultrasonography were 30, 95 and 53.42±18.12 mL, respectively. In total, 99 patients (26.1%) had received 5-ARI for at least three months before surgery. The mean decrease of the preoperative Hb in the postoperative 48th hour was 0.99±0.87 gr/dL. Only 9 patients (2.4%) received the transfusion of blood products (erythrocytes or fresh frozen plasma). The preoperative Hb level was inversely and significantly correlated with the decrease in postoperative Hb and the need for transfusion (p<0.05). The preoperative use of 5-ARI was not associated with postoperative decrease in Hb and the need for transfusion. The preoperative cut-off value of Hb for predicting a substantial decrease in Hb and transfusion need after M-TURP was calculated as 12.45 gr/dL with a sensitivity and specificity of 77.8% and 86.8%, respectively. Conclusion: M-TURP is still a safe and effective option in BPO treatment in developing countries. Importantly, we do not recommend the routine preoperative blood preparation in index patients with Hb level higher than 12.45 gr/dL.

Authors and Affiliations

Serkan Akan, Caner Ediz, Eymen Özer, Mehmet Pehlivanoğlu, Hasan Hüseyin Tavukçu, Kazım Kıymaz, Ömer Yılmaz

Keywords

Related Articles

5-Hydroxyuracil Incision Activity Varies According to the Histological Grade of Non-muscle-invasive Bladder Cancer

Objective: High levels of endonuclease III-like 1 (NTHL1) DNA glycosylase, which plays a role in the first step of the base excision repair pathway, has been related to cancer initiation and progression. 5-hydroxyuracil...

The Role of Adrenal Cortex-Sparing Surgery for Bilateral Masses in Three Cases

Pheochromocytoma are the functional adrenal lesions originating from the chromaffin cells. For the cases of pheochromocytoma observed in multiple endocrine neoplasia Type 2 and Von Hippel syndrome, the bilateral adrenal...

Transurethral Resection of the Bladder Tumor Success Rates of Surgeons and Possible Causes of Differences Between Locals and Refugees

Objective: In our study, we examined the success rates of our surgeons and the criteria that define the success, and tried to reveal the possible causes of the differences in the success rates of transurethral resection...

Effect of Multidisciplinary Approach in Diagnosis of Renal Sinus Fat Invasion in Renal Cell Cancer

Objective: In order to make the most appropriate treatment decision for kidney masses, accurate radiological evaluation is vital. In this study, we aimed to discuss how would be the concordance between a multidisciplinar...

Non-muscle Invasive Bladder Cancer: Identifying Patients to Consider Timely, Initial Cystectomy

Non-muscle invasive bladder cancer is a heterogeneous disease with widely varying risks of recurrence and progression to muscle invasion. Risk stratification within current treatment guidelines are an attempt to address...

Download PDF file
  • EP ID EP688794
  • DOI 10.4274/uob.galenos.2020.1655
  • Views 134
  • Downloads 0

How To Cite

Serkan Akan, Caner Ediz, Eymen Özer, Mehmet Pehlivanoğlu, Hasan Hüseyin Tavukçu, Kazım Kıymaz, Ömer Yılmaz (2020). Efficacy and Safety of Monopolar Transurethral Resection of the Prostate on Bleeding Control in the Treatment of Benign Prostatic Obstruction: Is It Still a Good Option in Developing Countries?. The Bulletin of Urooncology, 19(3), -. https://www.europub.co.uk/articles/-A-688794