Efficacy And Tolerability Of Different Antihypertensive Drugs In Hypertension Alone And Type II Diabetes with Hypertension Patients: A Prospective Comparative Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Hypertension in diabetes is of the most widespread substantial cardiovascular risk factor of importance in clinical practice. A prospective comparative study was conducted in General Medicine (OP) Department at Rajiv Gandhi Institute of Medical Sciences (RIMS) Hospital, Kadapa in 83 patients Kadapa to study the efficacy and tolerability of different antihypertensive drugs in hypertensive alone and in type-2 diabetic with hypertension patients. Efficacy was assessed based upon the patient's reading of blood pressure and tolerability based on the patient's complaint on each follow up. By comparing the mean reduction in SBP and DBP with all class of antihypertensive drugs we observed that combination therapy showed high reduction in both SBP and DBP than monotherapy. Atenolol was more effective than Amlodipine. We noticed the underutilization of diuretics in monotherapy and in combination therapy. Although it was first line therapy for hypertension according to JNC-VI & VII report.
Authors and Affiliations
Dr. S. Parveen, M. Sunil, T. S. Durga Prasad, Dr. M. Madhan Mohan Rao
Keywords
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- EP ID EP392403
- DOI 10.9790/3008-1206024653.
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