Efficacy observation of perioperative prognosis in patients with severe tricuspid regurgitation after transcatheter tricuspid valve replacement
Journal Title: Journal of Air Force Medical University - Year 2023, Vol 44, Issue 8
Abstract
Objective To investigate the perioperative prognostic effect of transcatheter tricuspid valve replacement (TTVR) in patients with severe tricuspid regurgitation ( TR) . Methods A retrospective analysis was performed on 10 patients with severe / extremely severe TR at high surgical risk in Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University from September 2020 to August 2022. Under general anesthesia, all patients underwent a transatrial surgical approach, with intraoperative transesophageal echocardiography (TEE) and X-ray guided implantation of LuX-Valve. The clinical data of patients before surgery, before discharge and 6 months after surgery were collected and analyzed. Results LuX-Valve was successfully implanted in all the 10 patients. The operation time was 140. 0 (120. 0, 172. 5) min, and the ICU stay time was 3. 0 (2. 0, 3. 5) d. After implantation, 9 patients had no or minimal paravalvular leakage, 1 patient had mild perivalvular leakage, and no other perioperative complications occurred in all patients. The results of 6-month follow-up showed that the number of patients with New York Heart Association functional Class II was higher than that before surgery (8 vs 0, P < 0. 01), and tricuspid annular plane systolic excursion was significantly improved [16. 4 (14. 1, 18. 0) mm vs 12. 5 (11. 5, 15. 0) mm, P < 0. 01]. In addition, the 6-min walking distance of all patients [360. 0 (315. 0, 390. 0) m vs 212. 5 (165. 0, 255. 0) m] and Kansas City Cardiomyopathy Questionnaire score [62 (60, 65) points vs 31 (27, 37) points] were significantly higher than those before surgery (P < 0. 01). Conclusion This study preliminarily confirms that the use of LuX-Valve for TTVR in patients with severe TR is a feasible and relatively safe approach, with reliable clinical outcomes. However, due to the difficulty of the surgery, intensive observation and close monitoring are required.
Authors and Affiliations
ZUO Qian, ZHAI Mengen, SU Jie, MAO Yu, JIN Ping, LIU Yang, YANG Jian
Keywords
Related Articles
- EP ID EP724935
- DOI -
- Views 45
- Downloads 0
Cannabinoid receptor agonist ACEA promotes myelin recovery after spinal cord injury by regulating IL-33
Objective To investigate the protective effect of activating cannabinoid type 1 receptor (CB1R) agonist ACEA in promoting myelin recovery after spinal cord injury (SCI) in mice, and to clarify the role of interleukin-33...
Gamified inhibitory control trainings based on mobile application
Objective To design a gamified inhibitory control training task based on mobile application and evaluate its training effect. Methods A gamified inhibitory control training task with classic Go / No-go task as the core...
A multicenter, double-blind, randomized placebo-controlled phase Ⅱ / Ⅲ clinical trial of meplazumab in the treatment of COVID-19
Objective Meplazumab is a humanized anti-CD147 IgG2 monoclonal antibody, which can inhibit the virus from invading human host cells by blocking the interaction between CD147 and the spike protein of severe acute respir...
Clinical characteristics and outcomes of carbapenem-resistant Klebsiella pneumoniae blood stream infections
Objective To explore the clinical characteristics, mortality rate, and related risk factors in patients with carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infections. Methods Clinical data of inpatients...
Recognition of high ruminant population based on natural language and EEG
Objective To investigate a new model that can be used to identify people with high rumination through the electroencephalogram (EEG) signal features induced by natural language, based on EEG technology. Methods A total...