Efficacy observation of perioperative prognosis in patients with severe tricuspid regurgitation after transcatheter tricuspid valve replacement
Journal Title: Journal of Air Force Medical University - Year 2023, Vol 44, Issue 8
Abstract
Objective To investigate the perioperative prognostic effect of transcatheter tricuspid valve replacement (TTVR) in patients with severe tricuspid regurgitation ( TR) . Methods A retrospective analysis was performed on 10 patients with severe / extremely severe TR at high surgical risk in Department of Cardiovascular Surgery, Xijing Hospital, Air Force Medical University from September 2020 to August 2022. Under general anesthesia, all patients underwent a transatrial surgical approach, with intraoperative transesophageal echocardiography (TEE) and X-ray guided implantation of LuX-Valve. The clinical data of patients before surgery, before discharge and 6 months after surgery were collected and analyzed. Results LuX-Valve was successfully implanted in all the 10 patients. The operation time was 140. 0 (120. 0, 172. 5) min, and the ICU stay time was 3. 0 (2. 0, 3. 5) d. After implantation, 9 patients had no or minimal paravalvular leakage, 1 patient had mild perivalvular leakage, and no other perioperative complications occurred in all patients. The results of 6-month follow-up showed that the number of patients with New York Heart Association functional Class II was higher than that before surgery (8 vs 0, P < 0. 01), and tricuspid annular plane systolic excursion was significantly improved [16. 4 (14. 1, 18. 0) mm vs 12. 5 (11. 5, 15. 0) mm, P < 0. 01]. In addition, the 6-min walking distance of all patients [360. 0 (315. 0, 390. 0) m vs 212. 5 (165. 0, 255. 0) m] and Kansas City Cardiomyopathy Questionnaire score [62 (60, 65) points vs 31 (27, 37) points] were significantly higher than those before surgery (P < 0. 01). Conclusion This study preliminarily confirms that the use of LuX-Valve for TTVR in patients with severe TR is a feasible and relatively safe approach, with reliable clinical outcomes. However, due to the difficulty of the surgery, intensive observation and close monitoring are required.
Authors and Affiliations
ZUO Qian, ZHAI Mengen, SU Jie, MAO Yu, JIN Ping, LIU Yang, YANG Jian
Keywords
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