Efficacy of Bromfenac in prevention of macular edema following cataract surgery in a tertiary care hospital in Salem district
Journal Title: Medpulse International Journal of Ophthalmology - Year 2019, Vol 10, Issue 2
Abstract
Background: Postoperative inflammation continues to be a cause of patient discomfort, delayed recovery, and in some cases, suboptimal visual results. Topical nonsteroidal anti-inflammatory drugs (NSAIDs) and steroid are commonly used in the management and prevention of noninfectious ocular inflammation following cataract surgery. Methods: A prospective study was carried out in 120 patients, In Department of ophthalmology over a period of six months from 2018November to2018 April a tertiary care hospital at Salem, Tamil Nadu. A suitable data collection form was designed to collect and document the data. The patients are to be selected as per selection criteria and their consents will be taken. Data were collected from the case sheets of medical records. Patients were selected in between the age of at least 18 and almost 80 are scheduled for routine cataract surgery. Patients were randomized to receive Loteprednol Etabonate or prednisolone acetate 4 times daily in addition to Bromfenac 0.09% and Moxifloxacin 0.6% after surgery. Visual acuity, IOP, and anterior chamber cell and flare intensity were assessed over 3 weeks after cataract surgery.Results: In patients who were treated with bromfenac the number of patients without significant macular thickness is 60 and with significant macular thickness is In patients who were treated with placebo the number of patients without significant macular thickness is 57 and with significant macular thickness is 3. This proves that the use of bromfenac as a post-operative treatment for the patients is much effective in the prevention of macular edema. The number of patients with raised IOP in different follow up visits on day-1 is 16,1,7and 2,in week-1 is 1,0,0,1, in week-2 is 1,0,0,1, in week-4 is 1,0,0,1,and in week-6 and week-8 is zero patients. This proves that use of bromfenac will not have any effect on IOP, because the number of patients with raised IOP on week-8 with different SLE findings was found to be nil when compared with day 1. Conclusion: From this study, we have concluded that bromfenac was found to be effective in the prevention of macular edema as none of the patients who were subjected to bromfenac developed macular edema. It can be considered to be safe and no complications developed in patients subjected to bromfenac following cataract surgery.
Authors and Affiliations
B Jayaprakash, R Rajesh Kannan, K Ezhilvendhan
Keywords
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- EP ID EP615127
- DOI 10.26611/10091025
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