Efficacy of Early N-Acetylcysteine in Rat Killer Paste Poisoning
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2019, Vol 6, Issue 10
Abstract
Introduction: Rat killer paste (yellow phosphorous) is one of the most common forms of poisoning in South India. It causes hepatotoxicity. No specific antidote has been found. Recently, N-acetylcysteine is used as supportive therapy in many cases of acute liver failure. Aim: This study aims to evaluate the effectiveness of early N-acetylcysteine in preventing the rat killer paste poisoning. Methods: Patients who ingested rat killer paste poison and age >12 years were included in the study. Patients having jaundice, liver disease, and age <12 years were excluded from the study. Results: Among 30 patients studied, five patients died, seven patients developed hepatitis, one patient developed acute kidney injury with hepatitis, and one patient developed hyponatremia. Conclusion: Early initiation of N-acetylcysteine had a significant impact in reducing mortality.
Authors and Affiliations
S Saravanan, B Karthik
Keywords
Related Articles
- EP ID EP483712
- DOI -
- Views 128
- Downloads 0
A Study on Noise-induced Hearing Loss of Police Constables
Introduction: Noise is defined as aperiodic complex sound. Noise is a common cause of hearing the loss in adults. Hearing loss due to injurious noise at the workplace is referred to as occupational noise-induced hearing...
Prevalence and Distribution of Different Types of Bone Defects in Chronic Periodontitis In Bagalkot Subjects - A Clinical Study
Background: Chronic destructive periodontitis involves resorption of the bone supporting the teeth. Various treatment aspects of this disease depend on the amount of alveolar bone remaining around the teeth. Hence, it is...
A Prospective Clinical Study on Types and Diagnostic Criteria of Fungal Rhinosinusitis used in Tertiary Teaching Hospital of Telangana
Background: Fungal rhinosinusitis (FRS) is a disease of a wide spectrum of immune and pathological responses and includes invasive, chronic, granulomatous, and allergic variants. Consensus on its terminology, pathogenesi...
Large Vesical Calculus Causing Labor Dystocia: A Case Report
Obstructed labor is a well-known clinical entity in maternity units, cephalopelvic disproportion being the most common cause. Here, we report a rare case of obstructed labor, where the cause was a large vesical calculus....
Comparative Study of Effectiveness of Short Course versus Long Course Antimicrobial Prophylaxis after Clean Orthopedic Surgery - A Prospective Study of 200 Patients
Introduction: Surgical site infection (SSI) is one of the most devastating complications associated with any surgical procedure. It is associated with prolonged morbidity, disability, and increased mortality. We assess t...