Efficacy of Intracuff Alkalinized 2% Lidocaine in Reducing Cough, Sore Throat And Hoarseness During Emergence in Smokers Undergoing Laparoscopic Surgery
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Background: Cough causes various complications during emergence from general anaesthesia especially in smokers. Objective of the Study: To assess the efficacy of intracuff alkalinized 2% lidocaine as compared to saline in reducing cough, sore throat and hoarseness during emergence in smokers undergoing laparoscopic surgery. Materials and Methods: 50 smoking patients undergoing laparoscopic surgery under general anesthesia including nitrous oxide (N2O) were enrolled. Patients were randomly allocated to receive either endotracheal tube intracuff 2% lidocaine plus 8.4% sodium bicarbonate (Group I, Study Group), or endotracheal tube intracuff 0.9% saline (Group II, Control Group). The endotracheal tube cuff was inflated to achieve a cuff pressure that prevented air leak during positive pressure ventilation. Incidence of emergence coughing, postoperative sore throat, and hoarseness were analyzed. The volume of inflation solution, the intracuff pressure, the duration of anesthesia, the time elapsed to extubation after discontinuation of anesthesia, and the volume of the inflation solution and the air withdrawn from the ETT cuff were also recorded. Results: Intracuff alkalinized 2% lidocaine was superior to saline in blunting emergence coughing (p<0.001). The incidence of sore throat was significantly lower in Group I at the post-anesthesia care unit (p=0.02). However, at 24 hours after extubation, sore throat incidence was similar in both the groups (p=0.07). Incidence of hoarseness was similar in both the groups. Intracuff pressure in the saline group increased with time while the intracuff pressure in the lidocaine group remained constant. Conclusion: Efficacy of intracuff alkalinized 2% lidocaine was superior to saline in reducing incidence of cough during emergence and preventing sore throat during the postoperative period in smokers
Authors and Affiliations
Vikas Gupta, Poonam Sharma, Madan .
Keywords
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- EP ID EP244337
- DOI 10.9790/0853-1610080105
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