EFFICACY OF SOLANUM TORVUM (BERRIES) ON CARRAGEENAN INDUCED RAT PAW EDEMA MODEL AN IN-VIVO ANTI-INFLAMMATORY STUDY
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 1
Abstract
Solanum torvum, commonly called as Hativekuri, is very popular as an anti-inflammatory medicine among the Tiwa communities of Morigaon district Assam, India. The methanolic extract of the raw berries of Solanum torvum was investigated for its anti inflammatory activity in animal model. The extract at different doses (300 and 600 mg/kg b.w.) used showed good anti inflammatory activity which has been done significantly, by the formation of edema induced by carrageenan. These results were also comparable to indomethacene, the reference drugs used in this study. The results from present study indicate the efficacy of the methanolic extract as a therapeutic agent in acute as well as chronic inflammatory properties. The phytochemical screening revealed the presence of active phytoconstituents i.e. flavonoids and phenolics, which may offer anti-inflammatory conditions. Thus it could be concluded that the methanolic extract of raw berries of Solanum torvum possess significant anti-inflammatory properties.
Authors and Affiliations
Bhagyashree Mahanta , Jogen Kalita
Keywords
Related Articles
- EP ID EP92518
- DOI -
- Views 131
- Downloads 0
DESIGNING OF COLON SPECIFIC MATRIX TABLET OF DIETHYL CARBAMAZINE CITRATE FOR THE TREATMENT OF FILARIASIS
The main aim of the study was to develop colon specific sustained release matrix tablets of diethyl carbamazine citrate (DEC), an anthelmintic for improving patient compliance, delivered to colon for its effective action...
DEVELOPMENT AND IN VITRO EVALUATION OF MOUTH DISSOLVING FILMS OF CAPTOPRIL
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme(ACE), the enzyme responsible for the conversion of angiotensin I (AT I) to angiotensinII (AT II). Captoprilmaybeusedinthetreatmentofhypertensi...
TRADITIONAL USES OF MEDICINAL PLANTS IN TREATING SKIN DISEASES IN NAGAPATTINAM DISTRICT OF TAMILNADU, INDIA
The present documented the traditional knowledge of Medicinal Plants species used in various type of skin diseases in Nagapattinam district. We have documented the use of 50 species belonging to 26 families. The informat...
THE EFFECTS OF HYPERICUM (HYPERICACEA) SPECIES ON MICROORGANISMS: A REVIEW
Hypericum L. is a medicinal plant which is commonly found on earth, has many varieties and the most frequently studied regarding its antimicrobial, antifungal and antiviral effects because of its biological and chemical...
ISOLATION AND CHARACTERIZATION OF MUCILAGE FROM THE FRUIT PULP OF FERONIA LIMONIA
Development of new excipients is time consuming, involves tedious procedures and is highly expensive. Instead, identification of new uses for the existing substances is relatively inexpensive and less time consuming. The...