Electrolyte disturbances in patients with acute exacerbation of bronchial asthma
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 9
Abstract
Introduction: Abnormal electrolyte levels in patients with bronchial asthma can be attributed to either low dietary intake or to adverse effects of asthma medications. This study was aimed at assessing the levels of serum electrolytes in patients with acute exacerbation of bronchial asthma and comparing them against non-asthmatic controls. Methodology: This observational study was conducted on patients who presented with complaints of acute exacerbation of bronchial asthma in the Emergency Department of Dr. DY Patil Medical College, Navi Mumbai. Laboratory investigations for biochemical parameters like serum sodium, potassium, calcium, magnesium and chloride were measured by using automated chemistry analyzer. During the study period a total of 50 asthmatic patients were compared against age and gender matched non-asthmatic controls. Results: Mean age of the patients in asthmatic and non-asthmatic group were 37.0 ± 8.7 and 38.4 ± 7.5 years respectively. Significantly lower mean serum calcium level was observed among asthmatics as compared to non-asthmatics (8.68 ± 1.02 mg/dl vs 9.59 ± 0.55 mg/dl, p value = 0.002). Similarly, significantly lower mean serum magnesium levels were found among asthmatic patients as compared to non-asthmatic controls (1.91 ± 0.54 mEq/L vs 2.43 ± 0.53, p value = 0.001). Furthermore, we observed a significantly higher proportion of patients with hypomagnesemia (62% vs 20%) and hypocalcemia (24% vs 2%) among asthmatics as compared to non-asthmatics. Conclusions: Calcium channel blockers and calcilytics may have a role in treatment of asthma and its symptoms.
Authors and Affiliations
Dr Sarang Patil
Keywords
Related Articles
- EP ID EP514949
- DOI -
- Views 68
- Downloads 0
To Evaluate the Maternal & Fetal Complications and Outcomes in PostTerm Pregnancy: An Institutional Based Study
Background: A post-terms pregnancy is a pregnancy that lasts longer than 42 weeks. Because there are some very serious risks for both mother and baby, your healthcare provider will follow a post-term pregnancy closely. T...
A 3 Year Study of Maternal Mortality at Government Medical College, Kota
Background: Maternal mortality continues to be a major public health problem in the developing world. Maternal mortality is a vital index of the effectiveness of obstetric services prevailing in a country. The present st...
Performance of Urinary Liver Type Fatty Acid Binding Protein in Predicting Acute Kidney Injury in Post Cardiac Catheterization
Acute kidney injury (AKI) is a common medical problem and is significantly associated with increasing morbidity and mortality. Contrast media (CM) is increasingly used in diagnostic and interventional procedures which re...
Efficacy of floor stabilization exercises and Swiss Ball exercises on patients with non-specific low back ache and to assess QOL of patients with low back ache- A comparative study
Study Objective: Comparison between floor stabilization exercises and swiss ball exercises efficacy on patients with non- specific low back ache. Study Design: Comparative study. Setting: All subjects were included from...
A Prospective Study on Blood Requisition and Utilization Practice in a Tertiary Care Teaching Hospital
Introduction: Blood component transfusions form a vital role in the resuscitation and management of both medical and surgical patients. Treating doctors tend to over-order blood components in surplus of utilization. Poli...