Endocrine Disrupting Chemicals and Obesity: A Review
Journal Title: IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS) - Year 2018, Vol 11, Issue 11
Abstract
Obesity is becoming a worldwide problem with almost half a billion of the world’s population now considered to be overweight or obese. The purpose of this review was to summarize that some environmental chemicals called endocrine-disrupting chemicals (EDC’s) may be able to interfere in the endocrine regulation of energy metabolism and adipose tissue structure and that there is a relationship between exposure to these chemicals and obesity in humans. This review examined the major sources of EDC’s, their routes into the human body, mechanism of action and how they alter metabolism thereby causing obesity. Also, the paper reviewed a few key experiments using animal models that have validated that these chemicals disrupt the endocrine system, thereby resulting in obesity.C
Authors and Affiliations
M. Yusuf, K. C. Swanson, M. L. Bauer
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