Endometriosis Research: Need for a Stem-Cell Based Experimental Model
Journal Title: Gynecology and Obstetrics Research – Open Journal - Year 2015, Vol 2, Issue 3
Abstract
Endometriosis is a complex disease and not a single phenotype can be delineated in available in vitro models. A comparative analysis of pluripotent stem cells in normal endometrium and endometriosis will give an understanding of status of biomarkers in endometrium and endometriosis, respectively. Highly pluripotent stem cells are critically important constituents of endometrium and contribute to ectopic endometriotic implants as reported in various studies. Because stem cells are undifferentiated and possess tremendous regenerative capacity, they are candidate cellular system for modeling endometriosis.
Authors and Affiliations
Parveen Parasar
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