Eosinophilic Granulomatosis with Polyangitis (Churg Strauss Syndrome) presenting as Guillain Barre Syndrome (GBS)- A Case Report
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 11
Abstract
Churg Strauss Syndrome (CSS) is a rare ANCA Associated Vasculitis (AAV) causes disseminated necrotizing vasculitis in patients with eosinophilia and Asthma. Initial presentation as Neuropathy is quite rare (15%).Usually Mono neuritis multiplex is the common presentation of Vasculitic neuropathy. Acute Neuropathy with GBS like initial presentation is extremely rare. There are only 6 case reports in literature. Here we present a 57 yr old male with history of asthma presenting with acute onset and progressive weakness of lower limbs followed by upper limbs with painful tingling and paresthesia over 3 weeks duration. On examination there was areflexic flaccid weakness of lower limbs and upper limbs both proximal and distal with distal sensory loss without any cranial nerve involvement. Investigations showed severe eosinophilia with proteinuria and urinary casts. Vasculitic workup showed high titre P-ANCA positivity. Nerve Conduction Studies showed severe axonal and demyelinating type of neuropathy effecting all four limbs. In view of vasculitis involving target organs patient was treated with pulse steroids and cyclophosphamide according to EUVAS Regimen. Patient showed good improvement in neurological deficits and proteinuria and is under regular follow up.
Authors and Affiliations
Praveen Kumar Yadav
Keywords
Related Articles
- EP ID EP525704
- DOI -
- Views 102
- Downloads 0
A Clinico-Epidemiological Study of Acute Diarrhoea in Under Five Children Admitted in a Tertiary Care Hospital in Western Maharashtra
Background: Diarrhoea has been defined in many ways, as an increased water content of stools, altered consistency, increased frequency or combinations of all these three. A lot has been studied regarding diarrhoea which...
Associate Professor in Physiology, JNMC Sawangi (M) Wardha, DMIMSU (DU), India
ABK is the metallic based herbal medicine, no scientific testimonial exist to conform its action and potential efficacy to proof the ancient siddhars’ quotation about Ayabirunkaraja katpam which is mentioned in reputed s...
Clinical Profile, Aetiology, and Short Term Outcome of Convulsive Status Epilepticus in Children in Eastern India
The study was done to assess the clinical profile, aetiology, neuroimaging pattern, short-term outcome and possible risk factors of status epilepticus (SE). A prospective study was carried out on convulsive status epilep...
Exodontia – A Review of Various Techniques
This review encompasses the various principles and techniques used in exodontia and also their advantages and disadvantages
Post Operative Infection in Surgical Wards and Factors Influencing the Infection Rate in Tertiary Care Hospital
A prospective study of 1428 surgical wounds was conducted. All the wounds were examined for presence of infection and those with infection were studied bacteriologic ally. The overall infection rate is 4% (58). Klebsiell...