Epidemiology of Guillain Barre Syndrome in North Western Part of Rajasthan
Journal Title: Indian Journal of Neurosciences - Year 2016, Vol 2, Issue 1
Abstract
Background: Guillain-Barre syndrome is an autoimmune disorder and is an important cause of acute flaccid paralysis. This study was carried out to determine the prevalence and epidemiology of Guillain Barre Syndrome. Methods: This is a retrospective study conducted in the Department of Paediatrics, Sardar Patel Medical College & A.G. Hospitals, Bikaner. All the cases of Acute Flaccid Paralysis are reported under the AFP surveillance Program. Records of all the patients of AFP in years 2012 to 2015 were analysed. Among these, cases diagnosed as GuillainBarre syndrome were taken into consideration. The diagnosis was made on the basis of history, clinical examination, CSF studies, nerve conduction velocity and MRI of spinal cord when required. All the collected data was tabulated and stastically analyzed by using SPSS software. Results: In our study, Total 130 cases were reported as having Acute Flaccid Paralysis in years 2012 to 2015.Of these 54 cases were diagnosed to have Guillain-Barre syndrome. In our study prevalence of GBS was 41.5%. Most cases were in the age range of 13-60 months. In these study males (68.5%) were more affected than girls (31.5%). Lower limb weakness is the common presentation in GBS patients. Out of 54 reported GBS cases, 9 cases were expired. Conclusion: Future research needs to be focused on developing accurate diagnostic methods as well as protocols to identify at-risk patients. The role of immunotherapy in patients with GBS needs to be fully established, and effective therapies are yet to be developed.
Authors and Affiliations
Nagaraj Niranjan, Swami Sarika, Berwal Pramod k, Sharma Manjulatha, Chaudhary Lokesh
Keywords
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