Etiologyof Clinically Failure Cases of Onychomycosis in a Tertiary Care Hospital in India.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 12
Abstract
Onychomycosis is often associated with chronicity,therapeutic difficulties and recurrence after healing leading to clinical failure and such casesare increasing in very rapid pace. In this background the present retrospective, observational study aimed to have an etiological review of such cases.The“studygroup”consistedof non-repeating,consecutive 92 patients who werediagnosed cases of onychomycosis and developed persistent lesions or recurrence after use of oral and / or topical antifungal agents continuously or intermittently for a period of> 12 months in toe nail infections and 6 months in finger nails. A control group was also formed with those who came for the first time with suspected onychomycosis and never applied any medicine. In history age, sex, literacy level,occupations, site of lesions, mode of using antifungal medicines and comorbid conditionswere enquired about.Standard laboratory procedures were performed for phenotypic identification of fungi.The highest number of cases (22.83%) were reported in 41-50 years age group.The maximum number of females(15.22%) were in 21-30 years and males(14.13% )were in 41- 50 years group. The highest number of patients had middleschool level educational qualification and housewives were highest occupational group.Only two female patients had psoriasis of nails and one male patient was diabetic and none had fungal infection in other parts of the body .34 patients followed the direction of dermatologists strictly and rest 58 patients used medicines inappropriately.Out of 92 isolates culture positive cases were 70 and of that 35 were dermatophytes and rest 35 were non dermatophyte moulds and candida species.Trichophytonviolaceum was most prevalent dermatophyte,Fusariumsolani as NDMs ,Candida albicans among yeasts and bipolaris andcurvularia in phaeoid group.
Authors and Affiliations
Anita Nandi (Mitra), Riya Sarker, Meghna Banerjee, Manideepa Sen Gupta
Keywords
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- EP ID EP423839
- DOI 10.9790/0853-1712060109.
- Views 62
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