Evaluation of Analgesic and Antimicrobial potential of Hydroalcoholic extract of leaves of Coleus aromaticus in albino mice
Journal Title: The Journal of Phytopharmacology - Year 2013, Vol 2, Issue 3
Abstract
The study describes the biological activity of the dried leaves of Coleus aromaticus belong to the family Lamiacea. Successive extraction was carried out for identification of the suitable solvent for furthr extraction. Phytochemical investigation was carried out for various solvent extracts as per their polarity. The dried powder of the plant was extracted with alcohol and water. The hydroalcoholic extract was then studied for analgesic and antimicrobial activity. The analgesic activity was carried out by tail immersion method, pentazocine as standard drug. The hydro alcoholic extract of the crude drug was screened for its antimicrobial activity against the gram positive and gram negative bacteria and fungi. The results obtained were compared with the standard drug Ampicilline trihydrate and Amphoterecine B. The hydro alcoholic extract shows the mild to moderate zone of inhibition for the gram positive, gram negative bacteria and fungi (23.5mm, 20mm, and 20.4mm).
Authors and Affiliations
Chandana Majee, G. K. Das, Rupa Mazumder and G. S. Chakraborthy
Keywords
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