Evaluation of Antioxidant, Anti-inflammatory and Antimicrobial Potential of Aegel marmelos Fruit Pulp Extracts against Clinical Pathogens
Journal Title: International Journal of Experimental Research and Review - Year 2024, Vol 46, Issue 10
Abstract
In India, a wide range of medicinal plants are reported. Since ancient times, these medicinal plants have been used by people for the treatment of several diseases. Herbal medicines typically have fewer side effects compared to synthetic medicines, and they are also non-expensive. The aim of this study is to evaluate the antioxidant, in vitro anti-inflammatory activity through HRBC membrane stabilization, as well as the antimicrobial potential of fruit pulp extracts obtained from Aegle marmelos (A. marmelos). The antioxidant activity of the fruit pulp extracts was assessed using the DPPH assay. Various A. marmelos fruit pulp extracts viz., aqueous, chloroform, ethyl acetate, hexane, methanol and L-ascorbic acid were found to have IC50 values of 91.168 µg/mL, 153.22 µg/mL, 195.58 µg/mL, 164.741 µg/mL and 39.488 µg/mL, respectively, while for L-ascorbic acid (standard) it was 57.823 µg/mL. The anti-inflammatory activity of the fruit pulp extracts of aqueous, chloroform, ethyl acetate, hexane and methanol are also dependent on the concentrations. The hemp production (IC50) concentration was 99.761 µg/mL, 114.443 µg/mL, 167.423 µg/mL, 118.397 µg/mL and 23.244 µg/mL. Likewise, the antimicrobial activity of A. marmelos fruit pulp extracts demonstrated significant effects against clinical pathogens. Comparatively, the methanol fruit pulp extract of A. marmelos showed higher antimicrobial activity than that of the other four extracts; methanol fruit pulp extract contributed significantly to the development of antimicrobial properties. The findings of this study, thus, methanol fruit pulp extract, clearly showed that it had the strongest antioxidant, anti-inflammatory and antimicrobial activity when compared to the other four extracts.
Authors and Affiliations
Saranya A, Sivakumari K, Rajesh S, Shyamala Devi, Padmavathy K, Hemalatha M
Keywords
Related Articles
- EP ID EP754323
- DOI 10.52756/ijerr.2024.v46.005
- Views 28
- Downloads 0
Pharmacognostic Investigations of Impatiens balsamina Linn.
Herbal medicines are the first type of medical system ever developed for treatment. The increasing studies on medicinal plants influenced the construction of an unique herbal pharmacopoeia and transformed how it was proc...
TLBO-trained ANN-based Shunt Active Power Filter for Mitigation of Current Harmonics
The increased utilization of nonlinear devices is resulting in damage to power distribution infrastructure by introducing harmonics into power system networks, which in turn causes distortion in voltage and current signa...
Abundance and diversity of unicellular, filamentous cyanobacteria (BGA) and other higher algal genera in different rice fields of North 24 Parganas District in West Bengal, India
The distribution of unicellular and filamentous Blue green algae in relation to seasonal variation in rice fields in three major rice growing different blocks of North 24 parganas in west Bengal has been under taken. Pr...
Design and Implementation of a Dual-Axis Solar Tracking System with IoT-Enhanced Monitoring Using Arduino
The position of the sun varies over the day and with the seasons, making it difficult for conventional fixed solar panel systems to achieve optimum energy production. By reorienting the panels to face the sun, solar trac...
Prevalence of overweight and obesity among Bengalee urban adult men of North 24 Parganas, West Bengal, India
Obesity is the most common nutritional disorder in the developed as well as developing countries. It is the result of an incorrect energy balance leading to an increased storage of energy mainly as fat. At present, it is...