EVALUATION OF CARCINO EMBRYONIC ANTIGEN (CEA) AND CARBOHYDRATE ANTIGEN (CA19-9) IN MONITORING OF TREATMENT RESPONSE IN GASTROINTESTINAL CANCERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 51
Abstract
BACKGROUND Carcino Embryonic Antigen (CEA) and Carbohydrate Antigen 19-9 (CA 19-9) were two tumour markers frequently used in the diagnosis, and monitoring of treatment response of gastrointestinal cancers like colon, rectum, stomach, pancreas and gall bladder cancers. MATERIALS AND METHODS This study is a case-control study. 50 diagnosed and confirmed cases of gastrointestinal cancers attending the surgery outpatients department and wards of Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India from March 2015 to February 2018 form the study group. CEA and CA19-9 estimation was done before the start of any treatment, during treatment and after treatment; may it be Surgery, Radiotherapy or Chemotherapy. The usefulness of these two tumour markers, CEA and CA19-9 combined for monitoring the treatment response was evaluated. RESULTS It is found that the combined use of these two markers CEA and CA19-9 is much more useful for monitoring of treatment response in the patients of gastrointestinal cancers when compared to the use of CEA alone or CA19-9 alone. CONCLUSION It is found that the combined use of these two markers CEA and CA19-9 is much more useful for monitoring of treatment response in the patients of gastrointestinal cancers when compared to the use of CEA alone or CA19-9 alone.
Authors and Affiliations
Rosemary Vumkhoching, Yengkhom Sanatomba Singh, Dhanabir Thangjam, Ningombam Jitendra
Keywords
Related Articles
- EP ID EP550476
- DOI 10.14260/jemds/2018/1209
- Views 86
- Downloads 0
SIDS UNEXPECTED/UNEXPLAINED/UNDETERMINED/UNCLEAR IS INCORRECT
BACKGROUND The biggest unsolved medical mystery today is the worldwide sudden infant deaths. Due to lack of care, skill, knowledge and wilful negligence of doctors they are not able to diagnose the cause of sudden infant...
TREATMENT OF INFECTED NON-UNION OF LONG BONES WITH MONOLATERAL EXTERNAL FIXATION (LRS)
Infected non-union has been defined as a state of failure of union and persistent infection at the fracture site for 6-8months1 and union is not likely to occur without active intervention. Infected non-union has be...
STUDY OF PATTERN OF VISUAL IMPAIRMENT IN PATIENTS SEEKING VISUAL DISABILITY CERTIFICATE
PURPOSE To determine the severity and various causes of visual impairment in patients seeking visual disability certificate. METHODS Cross-sectional study of patients seeking visual disability certificate from N...
VILLOGLANDULAR PAPILLARY ADENOCARCINOMA OF THE UTERINE CERVIX- A RARE CASE REPORT
PRESENTATION OF CASE A 41-year-old lady came with the complaint of post-coital bleeding since five months. She had had two full term spontaneous vaginal deliveries and both children were alive and healthy. Her general p...
A STUDY ON AETIOLOGY AND OUTCOME OF SHOCK IN CHILDREN
BACKGROUND Shock is one of the most common paediatric emergencies with significant mortality if not recognized and treated early. There are five major categories of shock, of which septic shock is increasing in incidence...