EVALUATION OF CBNAAT IN THE DIAGNOSIS OF SMEAR NEGATIVE TUBERCULOSIS IN A TERTIARY CARE HOSPITAL
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 90
Abstract
BACKGROUND Tuberculosis is world’s one of the deadliest communicable diseases, which requires early diagnosis and treatment. As smear confirmation requires at least 10000 bacilli/mL and conventional culture methods take 4 - 8 weeks, nucleic acid amplification methods are better option for early diagnosis of the disease. MATERIALS AND METHODS In the present study, we evaluated the diagnostic yield of CBNAAT (Cartridge Based Nucleic Acid Amplification Technique) in the detection of Tuberculosis in smear negative patients attending Government General Hospital, Kurnool, Andhra Pradesh. RESULTS Out of the total 3157 suspected Tuberculosis cases 2850 were smear negative samples, out of which 353 samples were diagnosed as CBNAAT positive with 19 Rifampicin resistance cases. CONCLUSION From this study, NAA technique is found to be a better diagnostic method when compared to the microscopy.
Authors and Affiliations
Rachamadugu Hymavathi, Gundela Swarnalatha, Beldona Nagajyothi, Basireddy Srikanth Reddy
Keywords
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- EP ID EP278226
- DOI 10.14260/jemds/2017/1364
- Views 84
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