Evaluation of detection and drug resistance of Mycobacterium tuberculosis in patients in Łódzkie voivodeship in 2009-2013
Journal Title: Przegląd Epidemiologiczny - Year 2015, Vol 69, Issue 3
Abstract
STUDY AIM. Evaluation of detection and drug resistance of Mycobacterium tuberculosis in patients from the Łódzkie Voivodship in the period 2009 – 2013. MATERIAL AND METHODS. The data presented in the study include information obtained while diagnosing patients from the Łódzkie Voivodship in order to detect infections with Mycobacterium tuberculosis in the period 2009 – 2013. RESULTS. In 2009 – 2013 we analyzed clinical specimens for the purpose of detection of Mycobacterium tuberculosis. Tubercle bacilli were confirmed in 5621 specimens in 2196 patients; positive bacterioscopy results were observed in 1724 clinical specimens. In the study period 18 clinical specimens obtained from children contained tubercle bacilli. In the period 2009 – 2013 we noted multi-drug resistant (MDR) strain in 41 clinical specimens, which made up 1.8 % of strains with known results of drug-sensitivity. In 5 clinical specimens we observed extensively-drug resistant (XDR) strain, which made up 0.2 % of strains with known results of drugsensitiveness. 12 clinical specimens appeared to contain pre-XDR strain, which constituted 0.6 % of strains with known results of drug-sensitivity. SUMMARY AND CONCLUSIONS. Despite advances in the diagnostics and treatment of tuberculosis (TB) this diseases still poses a serious medical problem. The detection level in the period 2009 – 2013 is relatively unchanged, with regards to both bacterioscopy and culture methods. Thus, the laboratory detection of tuberculosis bacilli is similar. It directly results from the enforcement of strict procedures regarding the quality of specimens collected for microbiological purposes and the control of the performed tests, which contributes to a greater number of confirmed cases of TB. In the study period the number of new cases of the infectious diseases is variable. Only in children this number remains stable over the years. Researchers observe that tubercle bacilli are resistant to basic first-line treatment drugs. They also note the occurrence of MDR, pre-XDR and XDR strains. Hence, it is important to regularly and carefully monitor the sensitivity of Mycobacterium tuberculosis to antibiotics administered in a long-term anti-tuberculosis therapy.
Authors and Affiliations
Karol Majewski, Małgorzata Rybczyńska, Karolina Wódz
Keywords
Related Articles
- EP ID EP71954
- DOI -
- Views 85
- Downloads 0
Malaria w Polsce w 2013 roku
CEL. Ocena sytuacji epidemiologicznej malarii w Polsce w 2013 r w porównaniu z latami wcześniejszymi. MATERIAŁ I METODY. Ocenę przeprowadzono w oparciu o wyniki analizy indywidualnych raportów przesyłanych do NIZP-PZH pr...
HIV and AIDS in Poland in 2016 / Zakażenia HIV i zachorowania na AIDS w Polsce w 2016 roku
AIM: The aim of the study was to assess the epidemiological situation of newly diagnosed HIV infections and AIDS cases in Poland in 2016 in comparison to the previous years. MATERIALS AND METHODS: Descriptive analysis of...
Chickenpox in Poland in 2016 / Ospa wietrzna w Polsce w 2016 roku
BACKGROUND: Chickenpox is a common disease in Poland. Annually, between 160,000 and 220,000 cases are registered. On average, there is an increase in incidence every 4 years. Therefore, it is justified to use preventive...
Stan przyzębia i wybrane wykładniki stanu jamy ustnej Polaków w wieku od 65-74 lat
WSTĘP. Celem badań była ocena stanu przyzębia za pomocą wskaźnika CPI u mieszkańców dużych i małych miast w wieku od 65 do 74 lat i porównanie z wynikami wcześniejszych badań polskich i europejskich z XXI wieku. Ponadto...
Occurrence and clinical characteristics of hepatocellular carcinoma in the north-eastern Poland / Występowanie i cechy kliniczne raka wątrobowokomórkowego wśród chorych z regionu północno-wschodniej Polski
Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the third leading cause of cancerrelated mortality worldwide. Risk factors for this malignancy include liver cirrhosis, HBV or HCV infection, fatty l...