Abstract

Background: High sensitivity C reactive protein (hsCRP) is an inflammatory marker known to be related to smoking, obesity and cardiovascular disease. Aim: To estimate and compare serum hsCRPlevels in mild, moderate, and severe asthmatics and in normal subjects and to obtain a mathematical model describing the relationship between serum hsCRP levels and severity of asthma. Materials and methods: A stratified sample of 54 asthmatic patients within age group of 18-60 years and 15 healthy controls within 18-60 years were included in this study and classified according to GINA classification. Serum hsCRP levels were estimated by turbidometry method. Results: Mean hsCRP levels ranged from 1.5mg/L in normal subjects to 13.90 mg/L in severe asthmatics. Conclusion: Serum hsCRP levels were high in asthmatics as compared to normal subjects. On an average, the levels increased as the severity of asthma increased. However, the mean values of hsCRP showed no significant difference among mild, moderate & severe groups of asthma.

Authors and Affiliations