Evaluation of serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia
Journal Title: Turkish Journal of Obstetrics and Gynecology - Year 2019, Vol 16, Issue 2
Abstract
Objective: The aim of the study was to assess serum cathepsin B, D, and L concentrations in women with late-onset preeclampsia. Materials and Methods: One hundred forty pregnant women were enrolled in the study, of which 100 subjects were preeclamptic and 40 were healthy controls. Serum concentrations of cathepsin B, D, and L were measured and compared between the preeclamptic and control groups. Results: Cathepsin B and D concentrations were significantly higher in the preeclamptic group compared with the control group. There was no statistically significant difference between the groups in terms of cathepsin L concentrations. Cathepsin B concentrations were significantly higher in women with preeclampsia with severe features compared with those with preeclampsia alone. Conclusion: Women with late-onset preeclampsia have significantly higher serum cathepsin B and D concentrations than controls. Cathepsin B and D may be promising biomarkers in women with late-onset preeclampsia.
Authors and Affiliations
Gökçe Anık İlhan, Begüm Yıldızhan
Keywords
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- EP ID EP48869
- DOI 10.4274/tjod.galenos.2019.40460
- Views 327
- Downloads 0
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