EVALUATION OF THE EFFICACY OF INTRA-ARTICULAR INJ. MAGNESIUM SULPHATE IN COMBINATION WITH INJ. BUPIVACAINE FOR POST-OPERATIVE PAIN RELIEF FOLLOWING DIAGNOSTIC ARTHROSCOPY OF THE KNEE JOINT- A COMPARATIVE PROSPECTIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 39
Abstract
BACKGROUND Ambulatory arthroscopic knee surgery is now an established technique for the diagnosis and operative management of intraarticular lesions. However, it is sometimes associated with moderate-to-severe post-operative pain. The present study was undertaken to evaluate the efficacy of intraarticular Inj. Magnesium Sulphate as an adjuvant to Inj. Bupivacaine for post-operative pain relief following diagnostic arthroscopy of the knee joint. MATERIALS AND METHODS This randomised controlled trial study of 60 eligible, consenting, ASA I and II physical status patients of either sex, undergoing elective diagnostic knee arthroscopy were enrolled in the study. All the cases were conducted under general anaesthesia. The patients were randomly allocated under two groups. Group A was the Control Group who received intraarticular 20 mL Inj. Bupivacaine 0.5% in addition to 10 mL 0.9% normal saline, ten minutes before the release of tourniquet at the completion of the procedure. Group B was the Study Group who received intraarticular 20 mL Inj. Bupivacaine 0.5% in addition to 10 mL Inj. Magnesium Sulphate 10%, ten minutes before the release of tourniquet at the completion of the procedure. All the patients were successfully reversed, extubated and observed for post-operative pain relief assessed by VAS score > 4 until the requirement of rescue analgesic drug in the form of IV Inj. Tramadol Hydrochloride 1 mg/kg. RESULTS All 30 patients in Group B, i.e. case group who received Inj. Magnesium Sulphate along with Inj. Bupivacaine showed a three-fold increase in the analgesic duration post-operatively in comparison with the Control Group A, who received only Inj. Bupivacaine along with normal saline. The patients were highly satisfied with the quality of pain free period and no major complications were observed in either group. CONCLUSION The present study confirmed the fact that intraarticular administration of Magnesium Sulphate is highly effective as an adjuvant to Bupivacaine. This combination resulted in potentiating the analgesic duration of action post-operatively in patients undergoing diagnostic arthroscopy of the knee joint, which enabled them to undertake a fast-tracking course.
Authors and Affiliations
Champa Banavara Venkateshamurthy, Ravindra Channagere Gangappa, Gurudutta Karnalli Nagarajarao
Keywords
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- EP ID EP548138
- DOI 10.14260/jemds/2018/951
- Views 93
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