Evaluation of the Efficacy of Tamsulosin and Deflazacort versus Tamsulosin Alone in Expulsion of Lower Ureteric Stones in a Tertiary Center
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2019, Vol 6, Issue 10
Abstract
Introduction: Urolithiasis is a very common problem present. About 70% of all ureteric stones are found in the lower third of ureter. Many factors affect the modality of treatment such as setup available, type, size of stone and expertise of the surgeon. Extracorporeal shock wave lithotripsy and ureteroscopy and removal of stone are very effective, but they require the help of anesthetist. Ureter is to be stented, and the stent has to be removed later on. They are very costly and not without complications. Many pharmacological agents have been used for the expulsion of ureteric stones, for example, diclofenac, alkalizers, ketorolac, nifedipine, deflazacort, prazosin, silodosin, and tamsulosin. Materials and Methods: This prospective observational study was conducted in the Surgery Department at SGT Medical College. A total of 100 patients of distal ureteric stones of sizes 4–10 mm were taken in this study, divided into two groups of 50 patients each. Group I patients were given tamsulosin 0.4 mg and deflazacort 30 mg once in a day, Group II patients were given tamsulosin 0.4 mg once in a day. Treatment was for 10 days. Results: In Group I, the stones were expelled in 38 (76%) patients, while in Group II, 26 (52%) patients passed stones. This is statistically significant with P = 0.038. The median time for stone expulsion was 3 days in Group I and 11 days in Group II with P = 0.032. Conclusion: We have evaluated that medical expulsive therapy using tamsulosin alone is also effective and can be used in patients where steroids are contraindicated, but by adding deflazacort, it becomes very effective for management of distal ureteral calculi.
Authors and Affiliations
Alok Ranjan Sinha, Vikas Siwach
Keywords
Related Articles
- EP ID EP483701
- DOI -
- Views 141
- Downloads 0
Comparison of Pregabalin and Tramadol for Post-operative Pain Management in Patients Undergoing Lumbar Laminectomy
Introduction: Prevention and treatment of post-operative pain continue to be a major challenge in post-operative care. Opioid analgesics, with their well-known side effects, continue to represent a cornerstone in post-op...
Comparison of the Efficacy of Topical Natamycin 5% and Fluconazole 0.3% Eye Drop Therapy versus Topical Natamycin 5% Alone in Deep Fungal Keratitis in Garhwal Region of Uttarakhand, India
Aims: The study aims to compare the efficacy of topical natamycin 5% and fluconazole 0.3% eye drop therapy versus topical natamycin 5% alone in deep fungal keratitis. Study Design: A prospective, randomized, clinical stu...
Comparison of Effects of Laryngeal Mask Airway Supreme Cuff Inflation with Air, Air: Oxygen Mixture, and Oxygen: Nitrous Oxide Mixture in Adults: A Randomized Double-blind Study
Introduction: Laryngeal mask airway (LMA) cuff pressure has been implicated as a prime reason for post-operative sore throat. LMA cuff pressure increases when the air is used for the cuff inflation during oxygen: Nitrous...
Prevalence of Thrombophilia in Patients with Adverse Pregnancy Outcome
Background: Thrombophilia is hereditary and acquired conditions that predispose the patients to thrombosis. Pregnancy is hypercoagulable state. The tendency to thrombosis develops rapidly in adverse conditions in pregnan...
A Qualitative Study on the Thoughts of Diabetics Against Initiation of Insulin Therapy
Background: Insulin therapy is often needed for proper glycemic control of type 2 diabetes mellitus as well as for other reasons, but the prescribing doctor very often encounters a vehement objection from the patient to...