EVALUATION OF THREE CASES WITH ACUTE CORONARY SYNDROME CAUSED BY CORONARY THROMBUS
Journal Title: Kocatepe Medical Journal - Year 2021, Vol 6, Issue 22
Abstract
Coronary thrombus causes reduced blood flow in patients with acute myocardial infarction. Our aim was to to contribute to the understanding of the mechanisms of coronary occlusion caused by thrombus, evaluating the histopathological characteristics of thrombi in three cases. Cases were diagnosed with ST elevation type of myocardial infarction by coronary angiography. Histopathological analysis of thrombi as well as immunohistochemical staining with PTX3 (pentraxin 3, an acute phase protein) and CD68 (a cytokine released from monocyte and macrophages) were performed. Blood levels of troponin and PTX3 were also evaluated. The PTX3 immunostaining score was high in all cases but it was not consistent with its blood level. The high PTX3 staining intensity in the case with normal PTX3 blood level may be the result of rapid local release of PTX3. Case with highest PTX3 blood level had another inflammatory disease that could have driven this increase. We suggest that PTX3 and CD68 immunostainings can be used as a marker in the histopathological evaluation of coronary thrombus.
Authors and Affiliations
Aysel GÜVEN BAĞLA, Meltem İÇKİN GÜLEN, Bahadır KIRILMAZ, Ertuğrul ERCAN
Keywords
Related Articles
- EP ID EP697206
- DOI https://doi.org/10.18229/kocatepetip.571532
- Views 111
- Downloads 0
FREQUENCY OF INCIDENTAL FINDINGS IN UNENHANCED ABDOMINAL COMPUTED TOMOGRAPHY FOR DIAGNOSIS OF URINERY SYSTEM STONE
OBJECTIVE: Urolithiasis is a common urinary tract pathology that can affect all age groups. All abdominal organs are imaged with computed tomography (CT) taken for urolithiasis. Therefore, renal and extrarenal incidental...
ASSESSMENT OF CASES ADMITTED TO THE NEONATAL INTENSIVE CARE UNIT WITH LOWER RESPIRATORY TRACT INFECTION
OBJECTIVE: The purpose of this study is to assess the clinical features, laboratory findings, diagnosis and treatments of neonates in the neonatal intensive care unit with a diagnosis of lower respiratory tract infection...
SPIRITUAL CARE APPROACH OF NURSES WORKING AT INTERNAL CLINICS
OBJECTIVE: With this descriptive and cross-sectional study, the aim was to assess spiritual care competency of the nurses who worked at internal clinics of a university hospital. MATERIAL AND METHODS: 171 nurses who wor...
DOES THE LEVEL AND SEVERITY OF INJURY AFFECT PATIENT SATISFACTION IN PATIENTS WITH CHRONIC SPINAL CORD INJURY UNDERGOING INPATIENT REHABILITATION ?
OBJECTIVE: This study aimed to investigate whether the level of satisfaction differed regarding the level and severity of injury in patients with chronic spinal cord injury (SCI) treated on an in-patient setting and whet...
INVESTIGATION OF KNOWLEDGE, ATTITUDES, BEHAVIORS ABOUT OCCUPATIONAL HEALTH AND SAFETY OF MEDICAL SCHOOL STUDENTS AND RESEARCH ASSISTANT PHYSICIANS
OBJECTIVE: Employees' occupational health and safety knowledge levels and practices have an important place in reducing the risk of occupational accidents. In this study, it was aimed to examine the knowledge, attitudes...