Evaluation of Wound Healing Activity of Aerial Parts of Ocimum Basilicum Linn and Bark of Ficus Benghalensis Linn and Their Polyherbal Formulation in Wound Healing Models
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 4
Abstract
A wound is break in the skin. Wound are usually caused by cuts or scalps, symptoms at wound or injury include swelling, stiffness, tenderness, discoloration skin tightness, itching and scar formation, two types of tissue injury:. Wound healing is a complex dynamic process. The main objective of this investigation is to evaluate wound healing activity of aerial part of Ocimum basilicum Linn and bark of Ficus benghalensis Linn and their polyherbal formulation in wound healing models. Various wound healing models like Excision, Incision, Dead space wound models were evaluated on the parameters like wound contraction, Epithelisation time, tensile strength, wet and dry granuloma weight and hydroxiproline estimation. The main objective of this investigation is to develop a product, which may give a wound healing property, and enhance wound healing process like increase the collagen synthesis, fibroblast proliferation, angiogenesis and epithelization, because products which are available in market are either antiseptic or antimicrobial.
Authors and Affiliations
Gaurav Dubey1, Satkar Prasad2, Sailesh Kumar Ghatuary, Anil Sarathe4 ,, Kalpana Prajapati5 ,, Reena Sheride6 .
Keywords
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- EP ID EP389912
- DOI 10.9790/3008-1204015056
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