Evaluation of Wound Healing Activity of Methanolic Extract of Tonna dolium (L.1758)
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 3
Abstract
Marine invertebrates offer a rich source of potential drugs with excellent biological activities. The present study was aimed at investigating the wound healing effect of methanolic extract of Tonna dolium (L.1758) using excision, incision and dead space wound model. Wound healing activity was evaluated in different concentrations prepared as simple ointment base BP using four groups of six Wistar albino rats in each model with povidone iodine (5%) as the standard drug. The wound healing was assessed by a rate of wound contraction, tensile strength and histological changes. Topical application of the methanolic extract ointments of T.dolium showed a significant and dose dependent effect on the healing process.
Authors and Affiliations
P. Subavathy1, R. D. Thilaga2 ,, A. Bavani Saraswathy3, S. Jeya Ruby
Keywords
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