Exposure to electromagnetic fields induces pathophysiological changes and oxidative stress in the cardiovascular system
Journal Title: Saudi Journal of Biomedical Research - Year 2017, Vol 2, Issue 5
Abstract
Abstract: This study aimed to highlight on the influence of exposure to electromagnetic fields (EMFs) on the cardiovascular system in humans and experimental animals, from the recent articles regarding the cardiovascular effects of exposure to EMFs. EMFs might produce a variety of adverse in vivo effects such as heart problems, chest pain, and cardiovascular system disorders. Previous studies showed that an association between elevated magnetic field exposure and mortality of employer in electric utility industry jobs from arrhythmia-related causes and acute myocardial infarction influence heart rate variability by changing autonomic balance. EMF exposure can affect structure and function of cardiovascular system and may facilitate myocardial infarction by nuclear changing of cardiomyocytes. Exposure to EMFs induced pain or pressure in the chest area, heart palpitations, and/or an irregular heart beat. The symptoms resemble a heart attack and thus contribute to even more anxiety. Also, exposure to EMFs caused highly significant increases in the activeties of serum creatinine phosphokinase, lactate dehydrogenase and aspartate amino-transferase enzymes, and decreases in plasma calcium level and total anti-oxidant capacity. Rats exposed to EMF showed increases in blood pressure, the absolute and relative whole heart and left ventricular weights. On the other hand, the heart rate was significantly reduced in rats exposed to EMF. The ECG recording of expermental animals exposed to EMF showed a significantly higher R and T voltages, increase in QRS duration, and prolonged P-R and QT-c intervals. A serious histopathological changes in the heart were seen in experimental animals exposed to EMFs, these changes includes increases the number of apoptotic cells, dark brown stain muscle fiber nuclei, marked cell vacuolation, hyperemia muscle fiber degeneration, distortion of some cardiac myocytes, mononuclear cellular infiltration and histological structure of the myocytes spaces were seen. Ultra structural of the myocardial tissue and sarcomere in experimental animals exposed to EMFs showed that lose of area in sarcomeres, irregular structural of myocardial cells, and ruptures of sarcomeres, lose of mitochondria cristae, blebs of mitochondria. It can be concluded that exposure of human and experimental animals to EMFs have been a negative effect on the heart and blood vessels by causing a histopathological changes and disturbances in the functions of the organs of the cardiovascular system. Keywords: Cardiovascular system, EMF, Heart function, Histopathology, Ultrastrucure, ECG, Oxidative stress.
Authors and Affiliations
Azab Elsayed Azab, Shaban Ali Ebrahim
Keywords
Related Articles
- EP ID EP387321
- DOI -
- Views 71
- Downloads 0
Difficulties in the diagnosis aetiology of A- β- ketosis-prone diabetes in a North-African adult
Abstract: Ketosis-prone diabetes (KPD) is a heterogeneous syndrome characterized by patients who present with diabetic ketoacidosis or unprovoked ketosis but do not necessarily have the typical phenotype of autoimmune ty...
Assessment of Erythrocyte Superoxide Dismutase as Biomarker of Oxidative Stress in Sudanese: Male Smokers in Khartoum State
Abstract: Oxidative stress plays an important role in the pathogenesis of some diseases. Smoking may enhance oxidative stress not only through the production of reactive oxygen radicals in smoke but also through weakenin...
Hormonal Therapy in Breast Cancer: Consideration of Pharmacogenetics
Abstract: Hormonal imbalance in postmenopausal women makes them susceptible to various menopausal symptoms and hormonal replacement therapy (HRT) is the treatment option for them. However, various concerns are involved w...
Low Back Pain in Athletes with Non-pharmacologic Care and Management
Abstract: Low back pain affects a large proportion of athletes. The purpose of this study was to perform a comprehensive review of literature regarding prevalence of low back pain, treatment, and rehabilitation with a sp...
Biological Samples as Potential Indicators of Heavy Metal Exposure in Coal Miners
Abstract: The impact of mining activities on environmental and human health has become a matter of serious concern. Human health and vegetation is affected by decline in the biological, physical, and chemical quality of...