Expression of hCG-β in Head and Neck Squamous Cell Carcinomas: A systematic Review.
Journal Title: International Journal of Dental Science and Innovative Research (IJDSIR) - Year 2019, Vol 2, Issue 1
Abstract
Head and Neck Squamous Cell Carcinoma (HNSCC) is a major public health issue all around the world. Establishment of an early and reliable biomarker with high sensitivity and specificity will enable early diagnoses of cancer and the best way for patient survival and improved quality of life. Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone normally produced by placental syncytiotrophoblast, which plays a critical role in implantation and maintenance of blastocyst. This hormone is known to be produced by neoplastic cells in tumors of trophoblastic origin. It has been widely studied tumor marker for ovarian tumors. The association of hCG-β in various head and neck tumors such as salivary gland, oral cavity, esophagus, thyroid and parathyroid has been reported. The current paper comprehensively studied the role of hCG-β in head and neck malignancies.
Authors and Affiliations
Dr. Jaya Singh
Keywords
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