Abstract

Bilineal leukemia is a very rare health condition, especially in pediatric patients; it is associated with poor prognosis, even without uniformity therapeutic criteria. Hereby, we present a 4-year-old boy, who debuted as T-cell lymphoblastic lymphoma, he initially received treatment induction, which was unanswered, further studies showed evidence of being bilinear leukemia (T-AML M5). He continued the AML induction therapy followed by four consolidations, achieving CR. In the absence of HLA-matched related donor, it was decided to make haploidentical transplant of his half-brother, with individual conditioning. Seven months post HSCT, he remains in CR. This case coincides with what is reported in the literature, concerning the poor response to chemotherapy, being the stem cell transplantation the only treatment option with curative intent; and in our country due to the high costs of a transplant not related to umbilical cord, we have chosen to start the program haploidentical HSCT to offer to these patients, a possible alternative healing.

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