Formulation and evaluation of floating tablets of Tapentadol HCl by direct compression method by using different swellable polymers and effervescent agents
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 2
Abstract
Floating tablets of Tapentadol Hcl were formulated by using swellabale polymers like carbomer, hypermellose, hydroxyl propyl cellulose, and gas forming agents like sodium bicarbonate. Drug excipient compatibility studies were conducted. Drug release profile was also studied. Effect of polymers on drug release kinetics was studied.
Authors and Affiliations
A. Srikanth, K. Narendra Kumar Reddy, K. Kanchanamala
Keywords
Related Articles
- EP ID EP33444
- DOI -
- Views 332
- Downloads 0
ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACTS OF NYCTANTHES ARBORTRISTIS AND NERIUM OLEANDER
In the present study, an attempt was made to investigate the anti-bacterial activity of Nyctanthes arbortristis and Nerium oleander. The crude drug powder extracts of the leaves of the above plants were taken for the s...
DRY EMULSION: A PROMISING DOSAGE FORM TO DELIVER LIPOPHILIC DRUG MOLECULES WITH IMPROVED STABILITY AND EFFECTIVENESS
Liquid emulsions have distinct advantages over the other oral dosage forms by improving the bio availability and by reducing the side effects, but the number of emulsion formulations currently in use are few compared w...
Design and development of Telmisartan transferosomes
The aim of this research activity is to formulate Soyalecithin based transfersomal nanoparticles for percutaneous administration of Telmisartan for better management against cardiovascular diseases. The I.R peaks obtai...
Neuroprotective profile of mulberry leaf extract in focal cerebral ischemia model in rats
The cerebral ischemia causes severe degree of oxidative stress as a result of reperfusion injury. An attempt has been made to analyze the preventive and curative potential of mulberry leaf extract, in focal cerebral is...
Efficacy and tolerability of corticosteroids in pediatric cancer chemotherapy patients
Efficacy and tolerability in the treatment of pediatric cancer was studied in the present investigation. Prednisone, Hydrocortisone, Dexamethasone, Prednisolone and Methyl prednisolone were used in the treatment. The p...