FORMULATION AND EVALUATION OF HERBAL EFFERVESCENT GRANULES INCORPORATED WITH MARTYNIA ANNUA EXTRACT
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 5
Abstract
The present research work is based on the formulation of herbal effervescent granules by incorporating the crude petroleum ether extract of martynia annua. The folklore of India widely uses this plant for treatment of various diseases and disorder. The dried leaves powder of the plant was extracted and subjected to preliminary chemical tests. Then it was formulated into efferevescent granules and then evaluated for various parameters like angle of repose, dissolution studies, and effervescent cessation time. The preliminary chemical studies show that the extract contains flavonoids, carbohydrate, alkaloids and glycoside. The formulated effervescent granules exhibited excellent flow properties which showed good angle of repose, carr’s index, Hausner’s ratio, bulk density and Tapped density.
Authors and Affiliations
Prakash Pandey*| Department of Pharmacognosy, Guru Ramdas Khalsa Institute of Science and Technology (Pharmacy), Jabalpur, M.P., India-482001, Prabhakar Sharma| Department of Pharmacognosy, Guru Ramdas Khalsa Institute of Science and Technology (Pharmacy), Jabalpur, M.P., India-482001, Ramchandra Gupta| Department of Pharmacognosy, Guru Ramdas Khalsa Institute of Science and Technology (Pharmacy), Jabalpur, M.P., India-482001, Ashish Garg| Department of Pharmaceutics, Guru Ramdas Khalsa Institute of Science and Technology (Pharmacy), Jabalpur, M.P., India-482001, Ajay Shukla| Department of Pharmachemistry, Guru Ramdas Khalsa Institute of Science and Technology (Pharmacy), Jabalpur, M.P., India-482001, Nitin Nema| Department of pharmaceutics, Sagar Institute of Research and Technology, Bhopal, M.P., India-462041, Anil Pasi| Department of pharmacology, College of Pharmacy, IPS Academy, Indore, M.P., India-452001
Keywords
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