FORMULATION AND EVALUATION OF LYCOPENE NIOSOMES WITH SPECIAL EMPHASIS ON STABILITY
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2017, Vol 3, Issue 3
Abstract
The objective of the work was to formulate and evaluate lycopene niosomes with special emphasis on stability. Niosomes was prepared by thin layer hydration and ether injection method using cholesterol, span 20, span 60. The drug-polymer incompatibility was carried out by FTIR studies. The formulated niosomes were then incorporated into 1% Carbopol gel for topical administration. Evaluation studies like drug content, entrapment efficiency, spredability, and in-vitro permeation release studies were performed. From the FTIR studies, the drug-polymers compatibility was confirmed, that the polymer did not interfere with the drug used. Entrapment efficiency varied from 58.56 to 98.92 %. The most ideal formulation was F3 since it showed good In vitro permeation release of 94.65 % at the end of 12 hours. From this study it could be concluded that the formulated Lycopene niosomal gel showed good and effective release.
Authors and Affiliations
Ganesh N. S.
Keywords
Related Articles
- EP ID EP649043
- DOI -
- Views 217
- Downloads 0
CONCEPTUAL STUDY OF LANGHANA AS TREATMENT IN AMAVASTHA OF VYADHIS
Ayurveda is an ancient science of life, i.e. the word “Ayurveda” itself says “Ayusho vedaha” that means veda of life is Ayurveda. This life science is very ancient estimated about 5000 years ago. Ayurveda blessed us with...
A CRITICAL UNDERSTANDING OF LOKA PURUSHA SAMYA VADA IN MAINTAINING THE INTEGRITY OF SUKRAVAHA SROTAS
Vajikarana tantra, the science which deals with the male reproductive system has a very crucial place in the present life scenario. In the fast life of present day, most of the people adopt to junk foods which lack many...
A REVIEW ON DUTIES AND LAWS RELATED TO MEDICAL PRACTITIONERS IN MEDICOLEGAL ASPECTS OF POISONING
Every poisoning case, whether acute or chronic, has medicolegal overtones. Basically there are three categories of medicolegal cases: accidental, suicidal, and homicidal. The majority constitutes either accidental or sui...
OJA: THE CONCEPT OF VYADHISHAMATVA (IMMUNITY) IN AYURVEDA
The concept of immunity in Ayurveda is a captivating and many faceted subjects. It is interesting to observe that the ancient Ayurvedic texts show a vivid description of the foundations of immunology thousands of years a...
ASSOCIATION OF APPETITE, FUNCTIONAL AND PSYCHOSOCIAL STATUS WITH THE MALNUTRITION AMONG ELDERLY RESIDING IN OLD AGE HOMES
Malnutrition is a common phenomenon among the elderly and quite often related to psychological and functional problems. The objective of this study was to determine malnutrition risk and its association with appetite, fu...