Formulation and evaluation of transdermal patches of Irbesartan
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 3
Abstract
The purpose of the research was to develop matrix type transdermal therapeutic system containing irbesartan with different ratios of hydrophilic and hydrophobic polymeric concentration by the solvent evaporation technique. The prepared patched showed satisfactory physiochemical characteristics of weight uniformity, thickness, folding endurance, moisture absorption for stability of the formulation and drug content were uniform in all patches. In vitro study done by using Franz diffusion cell having cellophane membrane to determine the amount of drug present in the formulated patch. In different formulation on the basis of present study formulation F5 show satisfactory drug release pattern.
Authors and Affiliations
A. Srilakshmi, V. Ravi Teja, K. Lakshmi, M. Thippesh, Sk. Ummehani Salma, B. Nagendrababu
Keywords
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