Fungal endocarditis with right ventricular candidal mycetoma in a premature neonate
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2015, Vol 5, Issue 3
Abstract
Fungal mycetoma or endocarditis is rare in premature neonates and it is often associated with high mortality. In the majority of the cases diagnosis is made postmortem. Here we report a 30-week-old preterm neonate who developed Candida albicans blood stream infection complicated by endocarditis and subsequent mycetoma. Initially, this neonate had Klebsiella sepsis requiring multiple antibiotic courses. A peripherally inserted central venous catheter was used to give total parenteral nutrition. On day 24 of life, he developed candidemia, treated with 14 day course of fluconazole and shown improvement. Further, on day 60 of life he developed cholestasis, deranged liver function tests and persistent thrombocytopenia along with apnea, bradycardia and desaturations. Blood culture again grew again C. albicans Echocardiography showed large fungal vegetation on tricuspid valve with a mycetoma filling the right ventricle. He was treated with intravenous amphotericin B, fluconazole and supportive measures, but he deteriorated and succumbed after two weeks. J Microbiol Infect Dis 2015;5(3): 142-145 Key words: Prematureneonate, candida sepsis, endocarditis, mycetoma
Authors and Affiliations
Jayashree Purkayastha, Leslie Lewis, Ramesh Bhat Y, Morakhia Jwalit V, Ranjan Shetty K, Muhammad Najih L
Keywords
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- EP ID EP111837
- DOI 10.5799/ahinjs.02.2015.03.0194
- Views 117
- Downloads 0
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