Genetic characterization of the wboA gene from the predominant biovars of Brucella isolates in Iran.
Journal Title: Electronic Physician - Year 2015, Vol 7, Issue 6
Abstract
Brucella spp. are gram-negative, facultative intracellular bacteria pathogens responsible for brucellosis, a zoonotic disease that can cause abortion, fetal death, and genital infections in animals and undulant fever in humans. Lipopolysaccharide (LPS) is known as a major virulence factor of Brucella spp. The wboA gene is capable of encoding a glycosyltransferase that appears to play a major role in LPS biosynthesis. Hence, the characterization of this gene can help in the clarification of the pathogenicity of Brucella spp.
Authors and Affiliations
Afshar Etemady, Mohsen Mohammdi, Majid Esmaelizad, Saeed Alamian, Fatemeh Vahedi, Khosro Aghaeipour, Ali Mohammad Behrozikhah, Ebrahim Faghihloo, Davoud Afshar, Sajad Firuzyar, Arian Rahimi
Keywords
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- EP ID EP117886
- DOI 10.14661/1381
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