GLIOMATOSIS CEREBRI (GC), PRESENTATION, MANAGEMENT & PROGNOSTIC OVERVIEW.
Journal Title: INTERNATIONAL JOURNAL OF PURE MEDICAL RESEARCH - Year 2017, Vol 2, Issue 5
Abstract
Gliomatosis cerebri (GC) is a rare, inltrating glioma of brain & spinal cord. It is affects children, adult & elder age groups. Objective: To have an overview on the clinical presentation, management, prognosis & survival period of patients with GC. Material & methods: We retrospectively studied the clinical presentation & management and prognosis in 14 patients of gliomatosis cerebri between 2013 and 2016. The presentation is that of raised ICP, focal neurodecit & epilepsy. Results: All patients treated with radiotherapy, followed in few cases by chemotherapy. The survival time was not more than 2 years in all cases. The diagnosis is based on radiological MRI studies & histopathology. Treatment: Surgical treatment is not usual option due to wide spread neuraxis involvement. Radiation therapy & chemotherapy may give some survival benet. The outcome of the disease & the prognosis is poor & the survival period not exceed 24 months with the best combined chemotherapy & radiotherapy.
Authors and Affiliations
Dr. Raad Ahmed Hussein, Dr. Muhammed Hameed Faeadh. Al Jumaily, Dr. Rana Hani Mohammed Ali Al- Shaikh Hamed
Keywords
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