GLYCAEMIC REGULATORY PROPERTIES OF SRI LANKAN LOW GROWN ORTHODOX ORANGE PEKOE BLACK TEA (Camellia sinensis)
Journal Title: Int J of Pharm Res & Analy - Year 2014, Vol 4, Issue 3
Abstract
This study examined the glycaemia regulatory potential of Sri Lankan low grown orthodox Orange Pekoe (O.P.) grade black tea brew (BTB) which was made according to ISO 3103 specifications. Different doses of BTB [223 (equivalent to 1.5 cups), 446 (equivalent to 3 cups) and 1339 mg /kg (equivalent to 9 cups) ]were orally administered to normoglycaemic rats (N= 9-12/group) and their fasting, random and post parandial (after glucose and sucrose challenges) blood glucose levels were determined using standard procedures. The effect of BTB on amylase (N=3) and glucosidase activities (N=6) were also assessed spectrophotometrically in vitro. The results showed that, BTB impaired the rise in blood glucose level following both oral glucose and sucrose challenges. In vitro studies showed that BTB possess mild (but dose-dependent) antiamylase activity but no anti-glucosidase activity. It is concluded that Sri Lankan low grown orthodox O.P. grade black tea has the potential to be used as a beverage to regulate glycaemia /dysglycaemia by suppressing post parandial hyperglycaemia
Authors and Affiliations
Ratnasooriya WD , Jayakody JRAC1 , Muthunayake TBS1 , AbeysekeraWKSM , Ratnasooriya CDT3
Keywords
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