Haemodynamic effects of low dose Dexmedetomidine infusion in patients undergoing laparoscopic cholecystectomy –A randomized study

Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 5

Abstract

Laparoscopic surgery had several advantages over conventional surgery for the patient. Dexmedetomidine due to its distinct properties can be used as an anaesthetic adjuvant in the form of intravenous infusion. We studied the use of low dose dexmedetomidine infusion in laparoscopic surgery and its effect on hemodynamics, sedation scores and analgesic requirements. After the approval of the hospital ethics committee of Mahatma Gandhi Memorial Hospital Warangal, Telangana state 90 patients, aged 25 to 52 years, ASA grade I to II, and scheduled for laparoscopic cholecystectomy, were included in the study. Control Group C received normal saline0.9%, Group D1received dexmedetomidine 0.2 μg/kg/h and Group D2 received dexmedetomidine 0.4μg/kg/ h intravenously. There was no significant difference in preoperative hemodynamic parameters between the groups. In control Group significant haemodynamic stress response was seen following laryngoscopy, tracheal intubation, creation of pneumoperitoneum and extubation. Index medetomidine groups, the haemodynamic response were significantly attenuated. In addition, dexmedetomidine provides lighter sedation and reduces the post‑operative analgesic requirements without any significant adverse effects. Dexmedetomidine 0.4mcg/kg/h was significantly more effective than 0.2mcg/kg/h and control group. Keywords: Laparoscopy, Cholecystectomy, Dexmedetomidine, Haemodynamic response, Analgesia.

Authors and Affiliations

Laxmi Narsaiah G, Murali. CH, Srinivasa Rao. B, Praveen Kumar. D, Sravan Kumar. G

Keywords

Related Articles

Infection by Dipylidiumcaninum in a child: First case report from north India

Abstract: Dipylidiumcaninum is also called as cucumber tapeworm or the double pore tapeworm. The natural lifecycle of Dipylidiasis infection occurs in cats and dogs. Humans are occasionally infected and are rarely repor...

Study of Carotid Doppler findings and risk factors in patients presenting with Ischemic stroke

Abstract: Atherosclerotic disease of carotid arteries outside the cranial cavity has been recognised as an important cause of ischemic stroke. Colour Doppler study of the carotid arteries is being used as a primary metho...

Community Based screening for Susceptibility to Renal Failure (RF) among Relatives of diagnosed patients with RF in Hail region

The aim of the current study was to evaluate the susceptibility for renal failure among relatives of those with renal failure in Hail region, Kingdom of Saudi Arabia (KSA). This study included first degree relatives of 1...

A Clinical Study on Comparison of Magnitude of Obesity among Urban and Rural Adults of Kashmiri Population

This is a population based cross sectional study conducted over a period of one year from February-2009 to March 2010, the study was conducted in selected villages and one town of district Anantnag of Kashmir valley. Thi...

Half versus Full Vacuum Suction Drainage after Modified Radical Mastectomy for Breast Cancer -A Prospective Randomized Control Study

Abstract: Suction drains are routinely used after modified radical mastectomy (MRM) and is an important factor contributing to increased hospital stay. Negative suction is expected to drain the collection and reduce the...

Download PDF file
  • EP ID EP371311
  • DOI -
  • Views 99
  • Downloads 0

How To Cite

Laxmi Narsaiah G, Murali. CH, Srinivasa Rao. B, Praveen Kumar. D, Sravan Kumar. G (2016). Haemodynamic effects of low dose Dexmedetomidine infusion in patients undergoing laparoscopic cholecystectomy –A randomized study. Scholars Journal of Applied Medical Sciences, 4(5), 1736-1740. https://www.europub.co.uk/articles/-A-371311