Haemodynamic effects of low dose Dexmedetomidine infusion in patients undergoing laparoscopic cholecystectomy –A randomized study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 5
Abstract
Laparoscopic surgery had several advantages over conventional surgery for the patient. Dexmedetomidine due to its distinct properties can be used as an anaesthetic adjuvant in the form of intravenous infusion. We studied the use of low dose dexmedetomidine infusion in laparoscopic surgery and its effect on hemodynamics, sedation scores and analgesic requirements. After the approval of the hospital ethics committee of Mahatma Gandhi Memorial Hospital Warangal, Telangana state 90 patients, aged 25 to 52 years, ASA grade I to II, and scheduled for laparoscopic cholecystectomy, were included in the study. Control Group C received normal saline0.9%, Group D1received dexmedetomidine 0.2 μg/kg/h and Group D2 received dexmedetomidine 0.4μg/kg/ h intravenously. There was no significant difference in preoperative hemodynamic parameters between the groups. In control Group significant haemodynamic stress response was seen following laryngoscopy, tracheal intubation, creation of pneumoperitoneum and extubation. Index medetomidine groups, the haemodynamic response were significantly attenuated. In addition, dexmedetomidine provides lighter sedation and reduces the post‑operative analgesic requirements without any significant adverse effects. Dexmedetomidine 0.4mcg/kg/h was significantly more effective than 0.2mcg/kg/h and control group. Keywords: Laparoscopy, Cholecystectomy, Dexmedetomidine, Haemodynamic response, Analgesia.
Authors and Affiliations
Laxmi Narsaiah G, Murali. CH, Srinivasa Rao. B, Praveen Kumar. D, Sravan Kumar. G
Keywords
Related Articles
- EP ID EP371311
- DOI -
- Views 92
- Downloads 0
Changes in Bone Mineral Density in Indian Women: A Cross-Sectional Study
Abstract: Thirty million women in India suffer from osteoporosis, of which 50% are post-menopausal. WHO has predicted Asians to be largely affected by osteoporosis by the year 2050. An Observational study was carried out...
Laparoscopic Versus Mini-Laparotomy Cholecystectomy – A Comparative Study
In the recent decade, laparoscopic cholecystectomy has become the gold standard for the treatment of symptomatic cholelithiasis with advantages in regard to postoperative pain, hospital stay, early return to activities o...
A Prospective Study to Assess Changes in Pulmonary Function Tests in Patients of Spinal Deformity Treated by Halo-Pelvic Traction
Abstract:Respiratory function of patients with spinal deformities is likely to be abnormal and treatment is a surgical challenge in the presence of deranged pulmonary function. Halo-pelvic traction is a valuable alternat...
Clinical, epidemiological and diagnostic profile of patients with carcinoma lung - A clinical study
Abstract: The study included all cytologically proved cases as carcinoma lung admitted in Medical wards at a Medical College in southern India. Information obtained from each of these patients was entered in a proforma d...
Occult Hepatitis C Virus Infection in Chronic Kidney Disease on Hemodialysis
Abstract: Patients undergoing hemodialysis are prone to Hepatitis C Virus (HCV) infection. Elevation of serum Alanine Amino Transaminase (ALT) is suspected to correlate with the occult HCV infection. Our study is based o...