Healing Action of Passion Fruit and Pequi Creams on Induced Skin Lesions in Mice
Journal Title: International Journal of Business and Management Invention - Year 2017, Vol 6, Issue 7
Abstract
The use of plants to treat various diseases is very common in Brazil. Passion fruit (Passiflora edulis Sims) and pequi (Caryocar coriaceum Wittm) are rich in antioxidants and vitamin A and used to treat skin infections and inflammations by presenting, among others, analgesic and anti-inflammatory properties. This study aims to analyze the repairing effect of Passiflora edulis and Caryocar coriaceum cream on the healing of cutaneous lesions in mice. The present work had approval number 01/16 and is in accordance with the provisions of Law 11794/2008, Decree No. 6.899 / 2009 and the National Council for the Control of Animal Experimentation (CONCEA). Fifty-six mice of the Mus musculus variety were randomly assigned to 4 groups of 6 animals treated with Passiflora edulis, Fibrinase® and saline. At the end of the 7 day and 14 day cycle, the mice were euthanized with a barbiturate overdose. Results: There was a difference in favor of the healing of the experimental groups in relation to the control group in the 7th and 14th days regarding the reduction of inflammation. Conclusion: It can be concluded that the treatment with passionflower cream (Passiflora edulis) and pequi (Caryocar coriaceum) was effective in the healing process in cutaneous lesions, but a broader study is needed to better understand the mechanisms involved.
Authors and Affiliations
Eduardo Andrade Vasconcelos, Esmeralda Maria Lustosa Barros, Carla Cecília da Costa Almeida, Larena Virna Guimarães Souza, José Moacir Machado Neto, Manuela de Sousa Moura Fé, Sarah Izabelly Alves Lemos, Kellyanne Soares de Sousa, Marcello Alencar Silva
Keywords
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