Abstract

Aim: To study HRV parameters in Type II Diabetes mellitus and to compare in relation to duration. Materials and method: A total of 100 subjects in the age group of 30 to 70 years were included in the study of which 50 were diabetic patients and 50 were control groups. The study subjects of both sexes were divided in to three groups. Group I – 50 Controls, age and sex matched healthy individuals. Group II- 25 Type II diabetic patientswith disease duration less than 3 years of good glycemic control. Group III – 25 Type II diabetic patients with disease duration less than 3 years of poor glycemic control. HRV analysis is performed by measurement of successive RR interval variation and parameter of frequency domain measures such as LF/HF, LF, HF were analysed. Results: In our study it is seen that all HRV parameters were significantly decreased in Diabetes when compared to normal controls,but there is no significant difference in HRV parameters with regard to duration. Poor glycemic control and increased duration of diabetes are the central key factors for the development of autonomic neuropathy. The decreased HRV parameters recorded in the absence of predominant symptoms of autonomic dysfunction indicates the early subclinical autonomic neuropathy in diabetes.

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