Hematocrit Spectrum in Dengue: A Prospective Study
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 5, Issue 10
Abstract
Aim: Dengue occurs in epidemics in India, severe forms are lethal. Hematocrit aids in prognosis and effective management of dengue. Our study is to assess the impact of age and gender on hematocrit values, and the effect of varying hematocrit values as a prognostic indicator in dengue. Materials and Methods: A total of 132 serologically proven dengue cases were analyzed over 1 month in November 2016, along with hematocrit and relevant hematology data (obtained from analyzer). Results: The age range was 5 months to 65 years with male preponderance. Hematocrit ranged from 20.8% to 59.6% (mean 40.2%). Male showed lowest and highest hematocrit. 55% had hematocrit >40%, 27%, had >45%, 58% showed hemocrit above reference range for age and sex, 8% showed hematocrit more than/equal to 20% above the reference range. A higher proportion of males showed increased hematocrit overall. 56% with increased hematocrit over reference range were associated with thrombocytopenia (<1 lakh/cumm). A comparison of varying hematocrit values with reference range adjusted for age and sex showed a high proportion of false positive in males and false negative in children and females. Conclusion: Hematocrit is an effective, simple diagnostic and prognostic tool and helps in the early appropriate management of dengue; however, guidelines need to be established to increase its accuracy.
Authors and Affiliations
Anagha A Joshi, B N Divyashree, B R Gayathri
Keywords
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