Hemophagocytosis with Plasmodium Falciparum in Bone Marrow: A rare case report
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 7
Abstract
Hemophagocytic syndrome (HPS) has been associated with infections, hematological malignancies and autoimmune conditions. Malaria is rarely reported to cause HPS. We report a case of a 28-year-old female with fever, anaemia, generalized weakness and splenomegaly, high serum ferritin. Peripheral blood smear revealed pancytopenia along with gametocytes of plasmodium falciparum. Bone Marrow aspiration smears also revealed presence of falciparum gametocytes, pigment laden macrophages and macrophages exhibiting hemophagocytosis were also observed. This case report emphasizes the need for consideration of diagnosis of hemophagocytosis in plasmodium positive smear so as to provide timely diagnosis and prompt treatment to improve the clinical outcome.
Authors and Affiliations
Dr Deepti Agarwal
Keywords
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