Hepatitis C virus infection in patients and family members attending two primary care clinics in Puebla, Mexico
Journal Title: Annals of Hepatology - Year 2014, Vol 13, Issue 6
Abstract
Background. Approximately 180 million persons (~2.8%) globally are estimated to be infected by hepatitis C virus (HCV). HCV prevalence in Mexico has been estimated to be between 1.2 and 1.4%. The aim of present work was to determine the prevalence of HCV infection in patients and family members attending two primary care clinics in Puebla, Mexico. Material and methods. Patients and their accompanying family members in two clinics were invited to participate in this study between May and September 2010. Results. A total of 10,214 persons were included in the study; 120 (1.17%) persons were anti-HCV reactive. Of the reactive subjects, detection of viral RNA was determined in 114 subjects and 36 were positive (31%). The more frequent risk factors were having a family history of cirrhosis (33.1%) and having a blood transfusion prior to 1995 (29%). After a multiple logistic regression analysis only transfusion prior to 1995 resulted significant to HCV transmission (p = 0.004). The overall detected HCV genotypes were as follows: 1a (29%), 1b (48.5%), 2/2b (12.8%), and 3a (6.5%). Conclusion. The HCV prevalence in this population is in agreement with previous studies in other regions of Mexico.
Authors and Affiliations
Aurelio López-Colombo, Daniel Meléndez-Mena, Virginia Sedeño-Monge, José R. Camacho-Hernández, Eduardo Vázquez-Cruz, Eduardo R. Morales-Hernández, Francisca Sosa-Jurado, Luis Márquez-Domínguez, Gerardo Santos-López
Keywords
Related Articles
- EP ID EP78450
- DOI -
- Views 137
- Downloads 0
Contribution on the topic of hypovitaminosis D in chronic hepatitis C
Pedunculated hepatic focal nodular hyperplasia
Worldwide mortality from cirrhosis
Background/Aims: Cirrhosis mortality has registered large changes over the last few decades. Aim: To report worldwide mortality due to cirrhosis over the period 1980-2002. Methods: Age-standardized (world standard) cirrh...
Portal vein thrombosis in patients with cirrhosis: just a common finding or a predictor of poor outcome?
Background & Aims. It is unclear whether portal vein thrombosis (PVT) unrelated to malignancy is associated with reduced survival or it is an epiphenomenon of advanced cirrhosis. The objective of this study...
Outcome of early vs. deferred antiviral treatment for recurrent hepatitis C in liver transplant recipients
The optimal timing to treat recurrent hepatitis-C virus (HCV) after liver transplantation (LT) remains uncertain. We compared the outcome of early (acute phase) and deferred (chronic phase) antiviral treatment for recurr...