Hepatitis C virus infection in patients and family members attending two primary care clinics in Puebla, Mexico
Journal Title: Annals of Hepatology - Year 2014, Vol 13, Issue 6
Abstract
Background. Approximately 180 million persons (~2.8%) globally are estimated to be infected by hepatitis C virus (HCV). HCV prevalence in Mexico has been estimated to be between 1.2 and 1.4%. The aim of present work was to determine the prevalence of HCV infection in patients and family members attending two primary care clinics in Puebla, Mexico. Material and methods. Patients and their accompanying family members in two clinics were invited to participate in this study between May and September 2010. Results. A total of 10,214 persons were included in the study; 120 (1.17%) persons were anti-HCV reactive. Of the reactive subjects, detection of viral RNA was determined in 114 subjects and 36 were positive (31%). The more frequent risk factors were having a family history of cirrhosis (33.1%) and having a blood transfusion prior to 1995 (29%). After a multiple logistic regression analysis only transfusion prior to 1995 resulted significant to HCV transmission (p = 0.004). The overall detected HCV genotypes were as follows: 1a (29%), 1b (48.5%), 2/2b (12.8%), and 3a (6.5%). Conclusion. The HCV prevalence in this population is in agreement with previous studies in other regions of Mexico.
Authors and Affiliations
Aurelio López-Colombo, Daniel Meléndez-Mena, Virginia Sedeño-Monge, José R. Camacho-Hernández, Eduardo Vázquez-Cruz, Eduardo R. Morales-Hernández, Francisca Sosa-Jurado, Luis Márquez-Domínguez, Gerardo Santos-López
Keywords
Related Articles
- EP ID EP78450
- DOI -
- Views 136
- Downloads 0
Hepatic endometriosis
Hepatic immunohistochemistry of bile transporters in progressive familial intrahepatic cholestasis
Background. Diagnosis of progressive familial intrahepatic cholestasis (PFIC) is a challenging matter that involves the summation of clinical, laboratory, radiological, and liver histological parameters; in addition to...
Dorsal root ganglionopathy in a hepatitis C patient: a case report
We report an unusual clinical presentation of dorsal root ganglionopathy in a hepatitis C patient with negative cryoglobulins characterized by both motor and sensory symptoms. This mixed clinical picture in a hepatitis C...
Nutritional support in the treatment of chronic hepatic encephalopathy
The prevalence of under nutrition in cirrhotic patients is 61% and it usually progresses as the disease becomes more advanced. The deterioration in the nutritional status and its associated metabolic derangements has rai...
Prevention of hepatocellular carcinoma: a concise review of contemporary issues
Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer deaths in men. Due to differences in the prevalence of viral hepatitis, the incidence of HCC in low and middle income...