Histomorphological Spectrum of Uterine Lesions in Patients Presenting with Abnormal Uterine Bleeding: Experience from a Tertiary Care Centre in Rural Haryana
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 4
Abstract
Introduction: Abnormal uterine bleeding is the most common presenting complaint among women of all age groups attending the gynaecology out patient department. Abnormal uterine bleeding is a term used to describe any type of bleeding that does not fall within the normal ranges for amount, frequency, duration and cyclicity. Dysfunctional uterine bleeding is a clinical term used to describe abnormal uterine bleeding not attributable to any underlying organic lesions like Leiomyoma, Inflammation and Polyps. The causes of abnormal uterine bleeding vary with age. The present study was carried out to study the histomorphological spectrum of uterine lesions in women of all age groups presenting with abnormal uterine bleeding and to classify the lesions as Dysfunctional uterine bleeding or Organic causes. Materials and Methods: The retrospective study included a total of 163 specimens received either as endometrial curettings or hysterectomy specimens belonging to all the age groups (reproductive, perimenopausal and post menopausal), presenting with complaints of abnormal uterine bleeding was carried out in the Department of Pathology at a tertiary care centre in rural Haryana. Results: Maximum cases (39.26%) presenting with abnormal uterine bleeding were seen in the age group 31-40 years. Out of total 163 cases, there were 91 (55.82%) DUB cases, 69 (42.33%) were organic lesions and 3 (1.84%) cases were inadequate for opinion. Proliferative phase was seen in maximum cases of dysfunctional uterine bleeding (36/91 cases) and leiomyoma was the commonest pathology in organic lesions category (24/69 cases). Conclusion: Study of histomorphological pattern of the endometrium in patients of all the age groups presenting with abnormal uterine bleeding helps to diagnose and categorize the lesions as Dysfunctional uterine bleeding or Organic causes, to plan specific treatment modality, to assess therapeutic response and to rule out carcinoma.
Authors and Affiliations
Shweta Rana
Keywords
Related Articles
- EP ID EP471100
- DOI 10.21088/ijprp.2278.148X.6417.17
- Views 74
- Downloads 0
Immunohistochemical Expression of P53 and Ki-67 Antigen in Premalignant and Malignant Oral Lesions
Background: p53 protein is a product of TP53 tumor Suppressor gene. TP53 mutations leading to loss of function are the commonest type of genetic damage found in human cancers and oral squamous cell carcinomas, often prec...
Fibroepithelial Polyps at Unusual Sites with Review of Literature
B27ackground: Fibroepithelial polyps are common small protuberant benign lesions primarily developing in areas where the skin forms creases such as neck, axillae, and groin. They may also arise on the face, usually on th...
Rainbows of Ovarian Lesions in Department of Pathology in a Tertiary Care Hospital
Background: Histopathological examination remains the gold standard for diagnosis of ovarian tumours. Morphological diversity of ovarian tumours poses many challenges in diagnosis. It is important to have knowledge regar...
Analysis of Red Cell Profile: Red Cell Distribution Width, Hemoglobin, Mean Corpuscular Volume in Elderly Patients
Introduction: Red cell distribution width (RDW), a numeric measure of variability in the size of circulating erythrocytes is a routinely reported haematological parameter commonly part of complete blood cell count. RDW w...
Histopathological spectrum of adrenal gland lesions
Introduction: Suprarenal gland is a bipartite endocrine gland which is divided into adrenal cortex and adrenal medulla. Histopathological spectrum of adrenal lesions consist of adrenal cysts, adrenal myelolipoma, adrenal...